Biomedical Applications and Research Progress of Electrospinning Technology and Electrospinning Nanofibers

Yang, Junzheng

doi:10.14293/s2199-1006.1.sor-.ppofgwr.v1

Cited by 6 publications

(4 citation statements)

References 91 publications

(127 reference statements)

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“…The authors of this paper, Isaac et al (2017), observed improvements in the mechanical strength and dielectric strength with increase in degree of alignment of fibers [171]. Aligned fibers are greatly beneficial when they are used in applications including field effect transistors, gas and optical sensors, fiber reinforced composite materials, and tissue engineering [172,173]. Bashur (2009) discussed the application of aligned fibers in the field of tissue engineering [174].…”

Section: Applications Of Aligned Fibersmentioning

confidence: 93%

Synthesis And Characterization Of Nanomaterials

Anand

2024

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Nanomaterials are described as materials that include particles, either in an unbound form or as an aggregate or as an agglomeration, and where at least fifty percent of the particles in the number size distribution have one or more exterior dimensions that fall within the size range of one nanometer to one hundred nanometers. Nanomaterials may be considered natural, accidental, or produced. Not only do nanomaterials and their related bulk materials have morphological qualities that are distinct from one another, but they also have the potential to exhibit physicochemical properties that are distinct from one another. Nanomaterials that have been manufactured are considered to be essential components of innovations in a wide range of fields that have the potential to have a significant impact. These fields include energy generation and storage, electronics, photonics, diagnostics, integrated sensors, semiconductors, foods, textiles, structural materials, sunscreens, cosmetics, and coatings or drug delivery systems, as well as medical imaging equipment. Students, researchers, and engineers who are looking for methods to create and characterise nanostructures in detail are the target audience for this book.

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Section: Applications Of Aligned Fibersmentioning

confidence: 93%

Synthesis And Characterization Of Nanomaterials

Anand

2024

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“…One of the advantages of this method is its ability to combine a variety of natural and synthetic polymers, along with inorganic materials, to effectively produce micro/nanocomposite fibers with the multifunctionality that they bring. Moreover, the high-surface area, porosity, and the capability of loading drugs or other biomolecules into the fibers make them useful for different applications [ 40 , 41 ]. In tissue engineering and biomedical applications, the fabrication of electrospun nanofibers using both synthetic and natural polymers has gained significant attention.…”

Section: Electro-fluid Dynamic Techniquesmentioning

confidence: 99%

Micro- and Nanostructured Fibrous Composites via Electro-Fluid Dynamics: Design and Applications for Brain

Renkler,

Scialla,

Russo

et al. 2024

Pharmaceutics

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The brain consists of an interconnected network of neurons tightly packed in the extracellular matrix (ECM) to form complex and heterogeneous composite tissue. According to recent biomimicry approaches that consider biological features as active components of biomaterials, designing a highly reproducible microenvironment for brain cells can represent a key tool for tissue repair and regeneration. Indeed, this is crucial to support cell growth, mitigate inflammation phenomena and provide adequate structural properties needed to support the damaged tissue, corroborating the activity of the vascular network and ultimately the functionality of neurons. In this context, electro-fluid dynamic techniques (EFDTs), i.e., electrospinning, electrospraying and related techniques, offer the opportunity to engineer a wide variety of composite substrates by integrating fibers, particles, and hydrogels at different scales—from several hundred microns down to tens of nanometers—for the generation of countless patterns of physical and biochemical cues suitable for influencing the in vitro response of coexistent brain cell populations mediated by the surrounding microenvironment. In this review, an overview of the different technological approaches—based on EFDTs—for engineering fibrous and/or particle-loaded composite substrates will be proposed. The second section of this review will primarily focus on describing current and future approaches to the use of composites for brain applications, ranging from therapeutic to diagnostic/theranostic use and from repair to regeneration, with the ultimate goal of providing insightful information to guide future research efforts toward the development of more efficient and reliable solutions.

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“…There are two major ways of drug delivery by electrospinning, either blending of drug with a polymer solution or chemically grafting the drug on the molecular structure of the polymer, and chemical grafting is possible with chemical bonding [ 102 ]. Rychter et al [ 103 ] produced fibers of poly-ε-caprolactone (PCL) and a composite of poly-ε-caprolactone (PCL) and cilostazol (CIL) by electrospinning, and they noticed that cilostazol (CIL)-loaded nano-membranes have vascular implant applications.…”

Section: Electrospun Nanofibers In the Biomedical Fieldmentioning

confidence: 99%

Electrospun Materials Based on Polymer and Biopolymer Blends—A Review

2023

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This review covers recent developments and progress in polymer and biopolymer blending and material preparation by electrospinning. Electrospinning is a technique that is used to produce nanofibers to improve the quality of membranes. Electrospun nanofibers are highly applicable in biomedical sciences, supercapacitors, and in water treatment following metal ion adsorption. The key affecting factors of electrospinning have been checked in the literature to obtain optimal conditions of the electrospinning process. Future research directions and outlooks have been suggested to think about innovative ideas for research in this field.

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Biomedical Applications and Research Progress of Electrospinning Technology and Electrospinning Nanofibers

Cited by 6 publications

References 91 publications

Synthesis And Characterization Of Nanomaterials

Synthesis And Characterization Of Nanomaterials

Micro- and Nanostructured Fibrous Composites via Electro-Fluid Dynamics: Design and Applications for Brain

Electrospun Materials Based on Polymer and Biopolymer Blends—A Review

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