Biomedical applications of mesoporous silica particles

Abstract

Hunter Thompson, and Jesse Gray. I truly appreciate all of your enthusiasm for chemistry and your contribution to this research. Finally, I would like to extend my deepest gratitude to a number of faculty and staff in the Chemistry Department for their varied assistance and support. Janet, Sharon, and Lindsay, I came to you with questions on a wide range of topics, and even if you didn't have the answer at your fingertips, you were always willing to search it out for me. To the instructors for whom I was a teaching assistant, particularly Assistant Professor Scott Shaw and Associate Professor Betsy Stone, I am grateful for the example you provided as teachers and as teaching mentors. And to the teaching laboratory support staff, Brian Morrison and Deb Williard, thank you so much for your practical and personal encouragement when I was frustrated.

Mesoporous Silica Nanoparticles as a System for Ciprofloxacin Drug Delivery; Kinetic of Adsorption and Releasing

“…The loading and release of two anticancer drugs 5-fluorouracil and 7hydroxycoumarin from MCM-48 nanoparticles were investigated and the results show that loading capacities of 5-fluorouracil and 7-hydroxycoumarin onto the nanoparticles of about 24 and 14 % were achieved, respectively (11). MPS nanoparticles have diameters in the range of a few hundred nanometers and two pore structures were synthesized , loaded with doxorubicin drug, and the release into a buffer solution was studied to determine the pore structure and type of MPS nanoparticles effect (12,13). The aim of this study is to synthesize MPS silica nanoparticles with a large surface area, high pore volume and regular distribution of pore sizes and to characterize the prepared mSiO 2 particles using different techniques.…”