Biomedical applications of natural rubber latex from the rubber tree Hevea brasiliensis

Guerra, Nayrim Brizuela; Pegorin, Giovana Sant’Ana; Boratto, Miguel H.; Barros, Natan Roberto de; Graeff, Carlos Frederico de Oliveira; Herculano, Rondinelli Donizetti

doi:10.1016/j.msec.2021.112126

Cited by 111 publications

(62 citation statements)

References 131 publications

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“…Due to the unique physical and chemical properties of NR, including resilience, elasticity, resistance to abrasion and impact, efficient heat dispersion, and malleability at cold temperatures, it is an industrially important polymeric material used to manufacture adhesives, tires, surgical gloves, health equipment and accessories, balloons, tubes, amongst others. The global consumption and production of NR in 2017 exceeded 1.3 million tons, mainly because, even though a large number of synthetic polymer counterparts are available now, only a few possess physical properties that are comparable to those of NR [ 75 , 76 ]. Nevertheless, the related production process is still manpower-intensive, decreasing its attractiveness whenever economic growth leads to demand for higher wages [ 77 ].…”

Section: It All Started With Natural Polymersmentioning

confidence: 99%

“…The pavement industry can be largely beneficiated from natural rubber, as it can be used as a bitumen modifier to prolong the lifespan of flexible pavements while aggregating environmental sustainability [ 82 ]. Finally, NR displays many properties that are compatible with the biomedical field, as in vitro biocompatibility, peptide- and angiogenesis-inducing activity for tissue repair, suitability for guided bone repair (useful for the regeneration of bones and teeth), as well as the ability to serve as a platform for the controlled delivery of active ingredients [ 75 ]. Other investigations related to the chemical modification of NR will be addressed again in the section dealing with furans and their aptitude to go through the thermo-reversible Diels–Alder reactions.…”

Section: It All Started With Natural Polymersmentioning

confidence: 99%

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Monomers and Macromolecular Materials from Renewable Resources: State of the Art and Perspectives

Gandini

Lacerda

2021

Molecules

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A progressively increasing concern about the environmental impacts of the whole polymer industry has boosted the design of less aggressive technologies that allow for the maximum use of carbon atoms, and reduced dependence on the fossil platform. Progresses related to the former approach are mostly based on the concept of the circular economy, which aims at a thorough use of raw materials, from production to disposal. The latter, however, has been considered a priority nowadays, as short-term biological processes can efficiently provide a myriad of chemicals for the polymer industry. Polymers from renewable resources are widely established in research and technology facilities from all over the world, and a broader consolidation of such materials is expected in a near future. Herein, an up-to-date overview of the most recent and relevant contributions dedicated to the production of monomers and polymers from biomass is presented. We provide some basic issues related to the preparation of polymers from renewable resources to discuss ongoing strategies that can be used to achieve original polymers and systems thereof.

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Section: It All Started With Natural Polymersmentioning

confidence: 99%

Section: It All Started With Natural Polymersmentioning

confidence: 99%

Monomers and Macromolecular Materials from Renewable Resources: State of the Art and Perspectives

Gandini

Lacerda

2021

Molecules

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“…Since 2018, the application of natural biopolymers in the medical field has mainly been used in drugs; for example, rubber latex from the natural rubber tree has good biocompatibility and has been shown to act as a controlled drug by enhancing the process of angiogenesis, guiding, and recruiting cells responsible for osteogenesis. The released solid matrix induces tissue repair (Guerra et al, 2021). In addition to being used for drugs, natural biopolymers can also be used as carriers for medical machinery (John and Shaiba, 2019) The field will continue to innovate and develop rapidly in the future.…”

Section: Medical Fieldmentioning

confidence: 99%

Global Trends in Natural Biopolymers in the 21st Century: A Scientometric Review

et al. 2022

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Since the 21st century, natural biopolymers have played an indispensable role in long-term global development strategies, and their research has shown a positive growth trend. However, these substantive scientific results are not conducive to our quick grasp of hotspots and insight into future directions and to understanding which local changes have occurred and which trend areas deserve more attention. Therefore, this study provides a new data-driven bibliometric analysis strategy and framework for mining the core content of massive bibliographic data, based on mathematical models VOS Viewer and CiteSpace software, aiming to understand the research prospects and opportunities of natural biopolymers. The United States is reported to be the most important contributor to research in this field, with numerous publications and active institutions; polymer science is the most popular subject category, but the further emphasis should be placed on interdisciplinary teamwork; mainstream research in this field is divided into five clusters of knowledge structures; since the explosion in the number of articles in 2018, researchers are mainly engaged in three fields: “medical field,” “biochemistry field,” and “food science fields.” Through an in-depth analysis of natural biopolymer research, this article provides a better understanding of trends emerging in the field over the past 22 years and can also serve as a reference for future research.

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“…Gathered milky sap or latex, which is the unprocessed rubber, contains proteins, carbohydrates, lipids, and inorganic salts in the main secreted polymer, cis‐1,4‐poly(isoprene). [ 281 ] By various cleaning processes of the gathered mixture, most of the non‐rubber ingredients can be removed. The remaining matter is the complex organic biopolymeric material, natural rubber, which has been used for industrial production since just before World War II.…”

Section: Sustainable Materials In Flexible Electronicsmentioning

confidence: 99%

Sustainable Macromolecular Materials in Flexible Electronics

Kılıçarslan

Bozyel

Gökcen

et al. 2022

Macro Materials & Eng

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With advances in electronics, the concept of flexible electronics has left traditional designs behind. Many concepts, such as sensors, transistors, soft robotics, data, and energy storage devices have begun to find more widespread and flexible areas of use. From this point of view, using environmentally friendly, abundant, and renewable natural materials that reduce carbon emissions in the production and disposal of these components is the first step toward the concept of sustainable flexible electronics. This review deals with the integration of sustainable natural materials obtained from plant, animal, and bacterial sources into sensors, displays, data storage, power generation, and soft robotic systems, with appropriate examples compiled from the last ten years. In addition, limitations in the use of sustainable materials as flexible electronic components and their potential for use in innovative electronic applications in the future are foreseen.

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Biomedical applications of natural rubber latex from the rubber tree Hevea brasiliensis

Cited by 111 publications

References 131 publications

Monomers and Macromolecular Materials from Renewable Resources: State of the Art and Perspectives

Monomers and Macromolecular Materials from Renewable Resources: State of the Art and Perspectives

Global Trends in Natural Biopolymers in the 21st Century: A Scientometric Review

Sustainable Macromolecular Materials in Flexible Electronics

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