2021
DOI: 10.3390/ma14237374
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Biomimetic Ceramic Composite: Characterization, Cell Response, and In Vivo Biocompatibility

Abstract: The present study aimed to synthesize biphasic calcium phosphate ceramics (CaPs) composed of β-tricalcium phosphate (β-TCP) and hydroxyapatite (HAp) from the propagated Scleractinian coral and dicalcium phosphate anhydrous using a solid-state reaction followed by heat treatment at a temperature of 1100 °C for 1 h to 7 days. The as-prepared coral and coral-derived biphasic CaPs samples were characterized through scanning electron microscopy, X-ray diffractometry, Fourier transform infrared spectroscopy, and Ram… Show more

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“…The synthesized BCP samples which tested negative for cytotoxic effects were further implanted in the rabbit model’s bone defects. This did not lead to any local adverse cellular or tissue reactions and instead depicted new bone formation and growth [ 22 ].…”
Section: Reviewmentioning
confidence: 99%
“…The synthesized BCP samples which tested negative for cytotoxic effects were further implanted in the rabbit model’s bone defects. This did not lead to any local adverse cellular or tissue reactions and instead depicted new bone formation and growth [ 22 ].…”
Section: Reviewmentioning
confidence: 99%