Biomimetic Copper Complex Containing Polymer Modified Electrode for Electrocatalytic Reduction of Oxygen

Abstract

The development of non-precious metal based electrocatalysts is highly desired for the oxygen reduction reaction (ORR) as alternates to noble metal based ORR electrocatalysts. Herein, we report mononulcear copper(II) complex [CuLbpy]ClO 4 (L=4-[(2-hydroxyphenylimino)methyl]benzoic acid) containing poly(allylamine.HCl) polymer (PAlACuLbpy) as an electrocatalyst for oxygen reduction reaction (ORR). PAlACuLbpy was mixed with poly(acrylic acid) and tetraethylortho silicate to prepare a composite and then deposited on the screen printed electrode surface. The modified electrode (PAlACuLbpy/PCE) is highly stable and showed a quasi-reversible redox behavior with E 1 / 2 =-0.2 V vs. Ag/AgCl(3 M KCl) in 0.1 M phosphate buffer at pH 7 under argon atmosphere. PAlACuLbpy/PCE exhibited a remarkable ORR activity with an onset potential of-0.1 V vs Ag/AgCl in 0.1 M PB (pH 7) in the presence of oxygen. The kinetics for ORR was studied by rotating disk voltammetry in neutral aqueous medium and the results indicated that the number of electrons involving in the ORR is four and the conversion products are water and hydrogen peroxide.

Voltammetric Determination of Droxidopa in the Presence of Tryptophan Using a Nanostructured Base Electrochemical Sensor

“…Electroanalytical methods have been more attractive in recent years because they are fast, simple, power efficient, inexpensive, accurate and highly sensitive [13][14][15][16][17][18]. Also, efforts have been made to modify the electrode surfaces for the purpose of lowering the overpotential, improving the sensitivity with high current density for effective enrichment of the desired substance and/or restraining the effect of interferences [19][20][21][22][23][24][25].…”

Polymer Amphiphiles for Photoregulated Anticancer Drug Delivery

“…Beyond the initially reported electron-rich alkenes, other moieties have emerged that undergo bond cleavage upon reaction with 1 O 2 , such as aminoacrylates, 24,25,26,27,28 alkoxyanthracenes, 29,30,31,32,33,34,35 and thioketals. 36,37 These classes of 1 O 2 -cleavable groups have been integrated into a range of degradable materials, including block copolymer micelles, 38,39 nanoparticles, 40 nanorods, 41 and vesicles. 42 Two principal methods exist that harness 1 O 2 -responsive linkers for applications in drug delivery: i) materials in which a prodrug is covalently linked through a 1 O 2 -clevable linker, 43 and ii) materials in which the drug is non-covalently trapped in a 1 O 2 -degradable carrier.…”

“…42 Two principal methods exist that harness 1 O 2 -responsive linkers for applications in drug delivery: i) materials in which a prodrug is covalently linked through a 1 O 2 -clevable linker, 43 and ii) materials in which the drug is non-covalently trapped in a 1 O 2 -degradable carrier. 39 Cleavage of linkages between hydrophobic and hydrophilic segments of amphiphiles provides an effective strategy to disrupt micelles. 39 Herein we report 1 O 2 -cleavable amphiphiles featuring alkoxyanthracene derivatives that bridge lipophilic and hydrophilic segments of polymers that assemble into photooxidatively degradable micelles.…”

“…39 Cleavage of linkages between hydrophobic and hydrophilic segments of amphiphiles provides an effective strategy to disrupt micelles. 39 Herein we report 1 O 2 -cleavable amphiphiles featuring alkoxyanthracene derivatives that bridge lipophilic and hydrophilic segments of polymers that assemble into photooxidatively degradable micelles. We prepared two amphiphilic polymers (9,10-C 18 PEG and 3,9-C 18 PEG), each consisting of a lipophilic stearyl chain and a hydrophilic polyethylene glycol (PEG) polymer connected through a 1 O 2 -cleavable linker (Figure 1).…”

Chitosan-Cu-salen/Carbon Nano-Composite Based Electrode for the Enzyme-less Electrochemical Sensing of Hydrogen Peroxide

“…Electrode modifications with redox-active moieties or a functional groups has gain a great interest, due to their fundamental importance in electrochemical catalysis and bio-sensing where transition metal complexes are used as an electro-catalyst due to their tunable redox potential [1][2][3]. Tetra dentate Schiff base ligands have been extensively used as catalysts in organic reactions and bio-mimetic enzymatic reactions [4,5]. Salen based electro-active complexes and their polymers have potential applications in the field of electro-catalysts, chemical sensors and optical devices [6,7].…”