Biomimetic polymeric transcatheter heart valve leaflets with low calcification and good regenerative ability

Wang, Xiaoxiao; Jiang, Hui; Zhang, Wenjie; Kong, Yuanyuan; Liu, Jing; Wang, Zhihong

doi:10.1039/d3tb00761h

Cited by 4 publications

(1 citation statement)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, our study deals with flying collisions by means of splitting customers into different groups; only one drone can serve the customers in the same group. In [56], the authors investigate the attention-based pointer network method to obtain multitrips for a drone for parcel delivery.…”

Section: Related Workmentioning

confidence: 99%

Drones Routing with Stochastic Demand

Dong

et al. 2023

Drones

View full text Add to dashboard Cite

Motivated by the increasing number of drones used for package delivery, we first study the problem of Multiple drOne collaborative Routing dEsign (MORE) in this article. That is, given a fixed number of drones and customers, determining the delivery trip for drones under capacity constraint with stochastic demand for customers such that the overall expected traveling cost is minimized. To address the MORE problem, we first prove that MORE falls into the realm of the classical vehicle routing problem with stochastic demand and then propose an effective algorithm for MORE. Next, we have a scheme of resplitting customers into different individual delivery trips while the stochastic demands are determined. Moreover, we consider a variety of MORE, MORE-TW, and design an effective algorithm to address it. We conduct simulation experiments for MORE to verify our theoretical findings. The results show that our algorithm outperforms other comparison algorithms by at least 79.60%.

show abstract

Section: Related Workmentioning

confidence: 99%

Drones Routing with Stochastic Demand

Dong

et al. 2023

Drones

View full text Add to dashboard Cite

show abstract

Electrospun Scaffolds are Not Necessarily Always Made of Nanofibers as Demonstrated by Polymeric Heart Valves for Tissue Engineering

Wang,

Gao,

Zhai

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

In the last 30 years, there have been nearly 60, 000 publications about electrospun nanofibers, but it is still unclear whether nanoscale fibers are really necessary for electrospun tissue engineering scaffolds. The present report puts forward this argument and reveals that compared with electrospun nanofibers, microfibers with diameter of about 3 μm (named as “oligo‐micro fiber” by us) is more appropriate for tissue engineering scaffolds owing to its better cell infiltration ability caused by larger pores with available nuclear deformation. To further increase pore sizes, electrospun poly(ε‐caprolactone) scaffolds were fabricated using latticed collectors with meshes. Fiber orientation led to sufficient mechanical strength albeit increased porosity. The latticed scaffolds exhibited good biocompatibility and improved cell infiltration. Under aortic conditions in vitro, the performances of latticed scaffolds were satisfactory in terms of the acute systolic hemodynamic functionality, except for the higher regurgitation fraction caused by the enlarged pores. This hierarchical electrospun scaffold with sparse fibers in macropores and oligo‐micro fibers in filaments provides new insight into the design of tissue engineering scaffolds, and tissue engineering may provide living heart valves with regenerative capabilities for patients with severe valve disease in the future.This article is protected by copyright. All rights reserved

show abstract

Recent advancements in polymeric heart valves: From basic research to clinical trials

Wang,

Fu,

Wang

et al. 2024

Materials Today Bio

View full text Add to dashboard Cite

Biomimetic polymeric transcatheter heart valve leaflets with low calcification and good regenerative ability

Abstract: Transcatheter aortic valve replacement (TAVR) technology is quickly advancing in clinic, however, as it expands to low-risk populations and younger patients (age <65 years), device durability is becoming a major challenge.

Cited by 4 publications

References 36 publications

Drones Routing with Stochastic Demand

Drones Routing with Stochastic Demand

Electrospun Scaffolds are Not Necessarily Always Made of Nanofibers as Demonstrated by Polymeric Heart Valves for Tissue Engineering

Recent advancements in polymeric heart valves: From basic research to clinical trials

Contact Info

Product

Resources

About