Biomolecular alterations in the early life stages of four food fish following acute exposure of Triclosan

Dar, Owias Iqbal; Aslam, Raouf; Sharma, Sunil; Jia, Ai‐Qun; Kaur, Arvinder; Faggio, Caterina

doi:10.1016/j.etap.2022.103820

Cited by 28 publications

(3 citation statements)

References 96 publications

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“…Glyphosate is the most widely used herbicide for farming applications in southern India, whereas chlorpyrifos [O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate] is the most widely used insecticide. Although there are numerous eco-friendly biopesticides, integrated pest management systems, neem-based biopesticides, and other natural pesticides available for IPM, farmers continue to rely on chemical pesticides due to their immediate effect and wide availability [11][12][13][14][15]. Once applied, a significant portion of pesticides in rice fields might reach surrounding aquatic areas, where they can have a detrimental effect on the biota.…”

Section: Introductionmentioning

confidence: 99%

Ecotoxicological Effects of Pesticides on Hematological Parameters and Oxidative Enzymes in Freshwater Catfish, Mystus keletius

Barathinivas¹,

Ramya²,

Neethirajan³

et al. 2022

Sustainability

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Hematological parameters and changes in stress-induced functionalities of cellular enzymes have been recognized as valuable tools for monitoring fish health and determining the toxic effects of pesticides. The present study was conducted to evaluate the toxic effect of selected pesticides viz., Ekalux (EC-25%), Impala (EC-55%), and Neemstar (EC-15%) on freshwater catfish Mystus keletius. Fish were exposed to sub-lethal concentrations (mg/L) of the selected pesticide for a period of 7, 14, 21, and 28 days. Hematological parameters viz., total erythrocyte (RBC), hemoglobin (Hb), and hematocrit (Ht) packed cell volume values decreased with an increase in exposure time to pesticides, whereas the values for parameters viz., leucocytes (WBC), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) increased significantly. A decrease in packed cell volume (PCV) and hemoglobin values coupled with decreased and deformed erythrocytes as signs of anemia were also observed. The effect of pesticides on RBC content was 1.43 (million/mm3) on day 7 and reduced to 1.18 (million/mm3) on days 14 and 21. A similar trend was found for Impala on RBC, which had an initial value of 1.36 (million/mm3) on day 7 and reached a value of 1.10 (million/mm3) on day 28. In contrast, the value of Neemstar decreased from 1.59 (million/mm3) on day 7 in control to 1.02 (million/mm3) on day 28. Data indicates that the order of toxic effect of pesticides recorded a maximum for Impala followed by Ekalux and Neemstar in the selected fish model. Likewise, the overall pattern of pesticidal activity on cellular enzymes (GDH, MDH, and SDH) recorded a maximum toxic effect for Impala followed by Ekalux and Neemstar. Results indicate that Chlorpyrifos pesticide-Impala evoked maximum toxic effect on selected tissues compared to the other two pesticides tested. Statistical analysis of the summative data using two way ANOVA was statistically significant (p-value < 0.001). The differences in the hematological parameters analyzed are attributed to the physiological acclimatization of the fish to the local conditions, which influences the energy metabolism and consequently determines the health status of the fish. Overall, Impala exhibited the highest pesticidal activity on cellular enzyme, followed by Ekalux and Neemstar. Results suggest that natural pesticides may be preferable for rice field application in terms of environmental safety.

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Section: Introductionmentioning

confidence: 99%

Ecotoxicological Effects of Pesticides on Hematological Parameters and Oxidative Enzymes in Freshwater Catfish, Mystus keletius

Barathinivas¹,

Ramya²,

Neethirajan³

et al. 2022

Sustainability

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“…Triclosan decreased zebrafish hatching rate and led to a series of malformations, such as cardiovascular malformation [ 68 ]. Additionally, otolith formation and eye and body pigmentation were disturbed along with growth restriction and pericardial edema [ 71 ]. Ninety-six-hour LC50 studies performed in zebrafish embryos and adults showed lethal concentrations of 0.42 and 0.34 mg/L, respectively [ 60 ].…”

Section: Discussionmentioning

confidence: 99%

A Short Review of the Toxicity of Dentifrices—Zebrafish Model as a Useful Tool in Ecotoxicological Studies

Stachurski,

Świątkowski,

Ciszewski

et al. 2023

IJMS

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This review aims to summarize the literature data regarding the effects of different toothpaste compounds in the zebrafish model. Danio rerio provides an insight into the mechanisms of the ecotoxicity of chemicals as well as an assessment of their fate in the environment to determine long-term environmental impact. The regular use of adequate toothpaste with safe active ingredients possessing anti-bacterial, anti-inflammatory, anti-oxidant, and regenerative properties is one of the most effective strategies for oral healthcare. In addition to water, a typical toothpaste consists of a variety of components, among which three are of predominant importance, i.e., abrasive substances, fluoride, and detergents. These ingredients provide healthy teeth, but their environmental impact on living organisms are often not well-known. Each of them can influence a higher level of organization: subcellular, cellular, tissue, organ, individual, and population. Therefore, it is very important that the properties of a chemical are detected before it is released into the environment to minimize damage. An important part of a chemical risk assessment is the estimation of the ecotoxicity of a compound. The zebrafish model has unique advantages in environmental ecotoxicity research and has been used to study vertebrate developmental biology. Among others, the advantages of this model include its external, visually accessible development, which allows for providing many experimental manipulations. The zebrafish has a significant genetic similarity with other vertebrates. Nevertheless, translating findings from zebrafish studies to human risk assessment requires careful consideration of these differences.

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“…It can be found in wastewater treatment plant effluents, surface water, and sediments due to its abundant use and incomplete removal by wastewater treatment plants [49], with a mean concentration between 0.0075 µg/L and 9.65 µg/L [50]. According to Dar et al [51], triclosan is responsible for the paralysis of many fish larvae, such as Cyprinus carpio, Ctenopharyngodon idella, Labeo rohita, and Cirrhinus mrigala, probably as a result of biochemical and transcriptomic alterations leading to oxidative stress, abnormalities in the normal function of the kidney and digestive system, and the impairment of normal metabolic processes [52].…”

Section: Common Compounds Inside Personal Care Productsmentioning

confidence: 99%

Get Rid of Marine Pollution: Bioremediation an Innovative, Attractive, and Successful Cleaning Strategy

et al. 2022

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Aquatic environmental pollution is a rather worrying and increasingly topical problem that requires the development and promotion of innovative and ecofriendly technologies. Pollutants in water include many common substances that can reach aquatic ecosystems through several pathways including wastewater, the atmosphere, ship discharges, and many other sources. Most of these toxic compounds are internalized by aquatic organisms, leading to bioaccumulation in tissues and reaching any level of the food chain through the biomagnification process. These mechanisms can develop into adverse effects on the physiology of organisms and biochemical processes of natural ecosystems, thus affecting animals, environments, and indirectly, human health. Innovative technologies to tackle marine pollution include bioremediation: a suitable, biological, and ecological approach that enhances the ability of micro-organisms to transform waste and toxic substances into forms that can be used by other organisms. In this context, micro-organisms appear to be essential for the detoxification of aquatic systems due to their metabolic activity. This review provides a careful analysis of the characteristics of the main pollutants that affect aquatic ecosystems, with a focus on their effects on organisms and environments. It also offers clear guidance on innovative biological strategies that can be employed to prevent, limit, and remediate anthropogenic influences on aquatic environments.

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Biomolecular alterations in the early life stages of four food fish following acute exposure of Triclosan

Cited by 28 publications

References 96 publications

Ecotoxicological Effects of Pesticides on Hematological Parameters and Oxidative Enzymes in Freshwater Catfish, Mystus keletius

Ecotoxicological Effects of Pesticides on Hematological Parameters and Oxidative Enzymes in Freshwater Catfish, Mystus keletius

A Short Review of the Toxicity of Dentifrices—Zebrafish Model as a Useful Tool in Ecotoxicological Studies

Get Rid of Marine Pollution: Bioremediation an Innovative, Attractive, and Successful Cleaning Strategy

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