“…Previous studies showed that increasing sodium phosphate buffer concentration (0.05 -1.0 M) increased lysozyme, stem bromelain protease and human serum albumin stability [15]. The thermal stability of lysozyme and hemoglobin decreased along the series TRIS (tris(hydroxymethyl)aminomethane) > TES (N-[tris (hydroxymethyl) methyl]-2-aminoethanesulfonic acid) ~ TAPS (N-[tris(hydroxymethyl)methyl] 3-aminopropanesulfonic acid) buffer [20]. The diffusion coefficient of monoclonal antibodies was buffer specific, decreasing in the order: citrate > succinate > phosphate > histidine ≈ acetate [21].…”