“…Unfortunately, only a few studies are available in literature concerning the use of biomarkers to assess the effects of exposure of the general population to emissions from waste management facilities [12]. This is probably due to the fact that this approach is not always feasible in epidemiologic studies, especially those involving large population groups, since biological monitoring presents several challenges, such as the low concentrations of substances to be measured in complex biological matrices and the difficulty in interpreting results due to the many exposure sources [23]. Finally, the need of extensive and detailed exposure studies aimed to clarify the potential link between illegal waste-disposal practices and the health impact on the population was recently discussed [24]; in particular, the need of more detailed epidemiological studies was outlined, which, however, would transpose in a very demanding strategy, assisted by multidisciplinary exposure assessment studies, including (i) the accurate mapping and characterization of all the potentially contaminated sites (i.e., the waste management sites, including the surrounding superficial water, groundwaters and soils which may be subjected to contaminations); (ii) human biomonitoring programs; and (iii) deeply-investigated individual exposure assessment.…”