Bioparticles assembled using low frequency vibration immune to evacuation drifts

Shao, Fenfen; Whitehill, James; Ng, Tuck Wah

doi:10.1063/1.4748276

Cited by 4 publications

(3 citation statements)

References 34 publications

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“…15,16 When driven in the longitudinal direction, various mode shapes for sessile drops have been observed, 17,18 leading to applications such as mixing and particle focusing. 19 Similar mode shapes have also been observed when the drop is driven in the lateral sense. 20 The need to provide a driving excitation to match the sessile drop's resonance frequency necessitates the availability of precision equipment to do so.…”

Section: ■ Introductionsupporting

confidence: 64%

“…Sessile and pendant liquid drops can be set into resonant vibration, and this has been known for some time. , When driven in the longitudinal direction, various mode shapes for sessile drops have been observed, , leading to applications such as mixing and particle focusing . Similar mode shapes have also been observed when the drop is driven in the lateral sense .…”

Section: Introductionmentioning

confidence: 90%

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Linear Stepper Actuation Driving Drop Resonance and Modifying Hysteresis

et al. 2016

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In this work, 2 μL water drops are placed on substrates that are created to have a circular hydrophilic region bounded by superhydrophobicity so that they exhibit high contact angles. When the substrate is translated by a linear stepper actuator, the random force components present in the actuator are shown to cause the drop to rock resonantly. When the substrate is translated downward at inclination angles of up to 6° with respect to the horizontal, the contact angle hysteresis increases progressively to a limiting condition. When the substrate is moved up at inclined angles, alternatively, the contact angle hysteresis increases initially to the limiting condition before it is progressively restored to its static state. These behaviors are accounted for by the reversible micro-Cassie to Wenzel wetting state transformations that are made possible by the hierarchical microscale and nanoscale structures present in the superhydrophobic regions.

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Section: ■ Introductionsupporting

confidence: 64%

Section: Introductionmentioning

confidence: 90%

Linear Stepper Actuation Driving Drop Resonance and Modifying Hysteresis

et al. 2016

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“…Simpler and inexpensive approaches have since been developed. One uses the flow generated in a capillary chamber developed on microscope coverslips (Lin et al, ; Siddiqi et al, ), while another applies sample vibration followed by evacuation flow in a tailored surface (Shao et al, ). In this work, we advance a method that offers a very fast means to collect particulate objects in suspensions (beads and live algal cells) as well as non‐particulate solutes (fluorescent proteins) in solution with the features of simplicity, low cost, and easy incorporation into the microscopic examination process.…”

Section: Introductionmentioning

confidence: 99%

MRT letter: Micro‐ to nanoscale sample collection for high throughput microscopy

Cheong

Liew

2013

Microscopy Res & Technique

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In high throughput microscopy, it is often assumed that the objects under investigation are fixed spatially. In addition, it is also presumed that the objects are sufficiently populated, otherwise there will be need to search through vast tracks of field of views before any recording can be done. The ability to collect objects at one location in the hydrated state is thus desirable and this is a challenge when the density of target objects in a sample is very low. In this work, we report that the generation of a squeezing flow from a circular coverslip compressing on suspensions is able to collect particulate (microbeads, fluorescent nanobeads and live algal cells) and non-particulate (EGFP) objects at the rim region of the coverslip. With a coverslip of 13 mm diameter, volumes between 2 µL and 4 µL were found to completely fill the coverslip without breaching the rims. Sample compression speeds between 100 µm/s and 1000 µm/s did not have any effect on object collection outcomes. In effect, the simple placement of coverslips on top the drop of sample by hand without a motorized translator was found to produce similar collection outcomes. Quantitative measurements confirmed that all the objects investigated were displaced and relocated at the rim regions to a very high degree.

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