2022
DOI: 10.3390/app12020666
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Biophysical and Biomechanical Effect of Low Intensity US Treatments on Pancreatic Adenocarcinoma 3D Cultures

Abstract: Current developments in medical technology have focused on therapeutic treatments that selectively and effectively address specific pathological areas, minimizing side effects on healthy tissues. In this regard, many procedures have been developed to provide non-invasive therapy, for example therapeutic ultrasound (US). In the medical field, in particular in cancer research, it has been observed how ultrasounds can cause cell death and inhibit cell proliferation of cancer cells, while preserving healthy ones w… Show more

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Cited by 3 publications
(3 citation statements)
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“…Overall, our study places itself along an entirely new line emerging from the possibility of using electromagnetic fields coupled with ultrasound for biomedical applications, as our group has recently demonstrated [22]. It would be of great interest to observe the treatment effects of this process on human bone marrow stromal stem cells.…”
Section: Discussionmentioning
confidence: 92%
“…Overall, our study places itself along an entirely new line emerging from the possibility of using electromagnetic fields coupled with ultrasound for biomedical applications, as our group has recently demonstrated [22]. It would be of great interest to observe the treatment effects of this process on human bone marrow stromal stem cells.…”
Section: Discussionmentioning
confidence: 92%
“…Regarding the in vitro experiments, it is possible, by means of the identification abbreviations given in the sumary tables presented in the Section 3 named Result, to derive information about each device. The coupling between the transducers and the stimulated cells in the in vivo tests is always performed by means of an aqueous or gel-like medium that allows proper coupling between the ultrasound transducer and the plate or multiwell containing the biological cultures [2]. Where in vivo tests have been conducted, the relative positioning of the transducer with respect to the mouse is associated with a number of related issues:…”
Section: Transducer Classification and Placement In Experimental Setupsmentioning
confidence: 99%
“…On the other hand, the main therapeutic areas in which ultrasound is used are lithotripsy, physiotherapeutics with musculoskeletal rehabilitation therapies, and tissue regeneration. One of the areas in which research is focusing, especially for cancer treatment, is ultrasound-induced apoptosis [2,3], which can be divided into the following:…”
Section: Introductionmentioning
confidence: 99%