Vegetation is an essential component of terrestrial ecosystems and supplies multiple ecosystem benefits and services. Several indices have been used to monitor changes in vegetation communities using remotely-sensed data. However, only a few studies have conducted a comparative analysis of different indices concerning vegetation greenness variation. Additionally, there have been oversights in assessing the change in greenness of evergreen woody species. In this study, we used the normalized difference vegetation index (NDVI), the enhanced vegetation index (EVI), the near-infrared reflectance of terrestrial vegetation (NIRv), and the leaf area index (LAI) data derived from MODIS data to examine spatial and temporal change in vegetation greenness in the growing season (May–September) and then evaluated the evergreen vegetation greenness change using winter (December–February) greenness using trend analysis and consistency assessment methods between 2000 and 2022 on the Tibetan Plateau, China. The results found that vegetation greenness increased in 80% of pixels during the growing season (northeastern, central-eastern, and northwestern regions). Nevertheless, a decline in the southwestern and central-southern areas was identified. Similar trends in greenness were also observed in winter in about 80% of pixels. Consistency analyses based on the four indexes showed that vegetation growth was enhanced by 29% and 30% of pixels in the growing season and winter, respectively. Further, there was relatively strong consistency among the different vegetation indexes, particularly between the NIRv and EVI. The LAI was less consistent with the other indexes. These findings emphasize the importance of selecting an appropriate index when monitoring long-term temporal trends over large spatial scales.