Biophysical investigation of liposome systems decorated with bioconjugated copolymers in the presence of amantadine

Abstract

Liposome-based technologies derived from lipids and polymers (e.g., PEGylated liposomes) have been recognized by their medical applications in nanomedicine. However, since such systems represent myriad challenges and may promote immune...

The disordering effect of SARMs on a biomembrane model

“…35–37 It has been reported that the drop evaporation process leads to the assembly of phospholipid mixtures for liposome preparation 35 and we have taken advantage of this methodology to successfully assemble biohybrid systems as described in previous works. 37–39 Here, to obtain DMPC/SARMs films, DMPC, and SARMs were weighted and hydrated together with deionized water at 40 °C under stirring (100–1000 rpm) and mixed for 5 h (1000 rpm) at 40 °C. After that, droplets of the DMPC/SARMs suspension were subjected to a drop evaporation process to generate DMPC/SARMs films.…”