Bioprocessing for biofuels

Blanch, Harvey W.

doi:10.1016/j.copbio.2011.10.002

Cited by 77 publications

(42 citation statements)

References 63 publications

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“…Moreover, large scale cultivation of algae can be carried out in controlled environments, such as photo bioreactors. The unique carbohydrate composition of algae presents a formative challenge for bioprocessing (5). As a consequence, there has been increasing interest in the discovery and development of enzymes that can depolymerize algal polysaccharides into fermentable monomeric sugars.…”

mentioning

confidence: 99%

Structure of a PL17 Family Alginate Lyase Demonstrates Functional Similarities among Exotype Depolymerases

Park

Jagtap

Nair

2014

Journal of Biological Chemistry

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Background: Exotype polysaccharide lyases can cleave glycosidic bonds to catabolize complex carbohydrates into simple monosaccharides. Results:The first characterization of a family 17 polysaccharide lyase (PL17) provides insights into the mechanism of alginate depolymerization. Conclusion:The structure of a PL17 enzyme illustrates unexpected similarities to other polysaccharide lyases despite a lack of sequence conservation.Significance: These studies demonstrate an unexpected evolutionary relationship among the polysaccharide lyases.

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mentioning

confidence: 99%

Structure of a PL17 Family Alginate Lyase Demonstrates Functional Similarities among Exotype Depolymerases

Park

Jagtap

Nair

2014

Journal of Biological Chemistry

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“…The scale of the PBR utilized for façade is limited by a number of factors Aesthetic design: A green façade will give extra attraction to a building such as; light dispersion coefficient, kl a , temperature, aeration and mixing [44][45][46]. These parameters are related with the operating conditions of the PBR.…”

Section: Combining Pbrs With Buildings: Applications For Sustainable mentioning

confidence: 99%

Photobioreactors for Sustainable Buildings

Köse¹,

Öncel²

2016

deufmd

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With the accelerated increase in World population, human activities leave bigger traces on environment and ecology, which are not always signs for good. Especially places where more concentrated populations live in, like metropolitans or bigger cities, these traces are more significant. Today, World population is more than 7 billions of people, and the individual or industrial activities of this population endanger the nature and many living systems. It is recognized that nature cannot handle this massive amount of negative accumulation and humans started to react to minimize the effects of the circumstances that harm nature. Renewable energy technologies are introduced for a better, green and sustainable energy consumption. With the idea of integrating microalgal biotechnology with renewable energy systems, a novel solution to energy problem has been introduced and a futuristic research area has been developed. Keywords

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“…Redox imbalances, i.e., the excess formation of NAD(P)H2, which is often observed in production hosts, need to be removed aerobically (by oxidation to water). Therefore, bioreactor aeration must be carefully adjusted to avoid excessive NAD(P)H 2 oxidation and, thus, a decrease of carbohydrate-to-hydrocarbon yields below theoretical maximum values corresponding to reduced overall process productivity [10]. Another way to improve productivity is to divide a bioprocess into a growth phase, where nutrients are employed to build up biomass rapidly, and a production phase, where nutrients are exclusively used for product formation.…”

Section: Industrial Production Strain Prerequisitesmentioning

confidence: 99%

“…These side products constituted up to mediated unwanted side reactions is the reduction of geraniol to citronellol by unspecific dehydrogenases of the whole-cell biocatalyst S. cerevisiae [96]. Concerning tolerance to hydrophobic and toxic molecules such as the monoterpene limonene, which, for example, may serve as a precursor for jet biofuels in the future [10,66], P. putida should have a clear advantage over monoterpene-sensitive S. cerevisiae [16,17,54]. However, the first de novo production of a monoterpene with P. putida has been described only very recently [53].…”

Section: Solvent-tolerant Hostsmentioning

confidence: 99%

Bioprocess Engineering for Microbial Synthesis and Conversion of Isoprenoids

Schewe

Mirata²,

Schrader

2015

Biotechnology of Isoprenoids

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Isoprenoids represent a natural product class essential to living organisms. Moreover, industrially relevant isoprenoid molecules cover a wide range of products such as pharmaceuticals, flavors and fragrances, or even biofuels. Their often complex structure makes chemical synthesis a difficult and expensive task and extraction from natural sources is typically low yielding. This has led to intense research for biotechnological production of isoprenoids by microbial de novo synthesis or biotransformation. Here, metabolic engineering, including synthetic biology approaches, is the key technology to develop efficient production strains in the first place. Bioprocess engineering, particularly in situ product removal (ISPR), is the second essential technology for the development of industrial-scale bioprocesses. A number of elaborate bioreactor and ISPR designs have been published to target the problems of isoprenoid synthesis and conversion, such as toxicity and product inhibition. However, despite the many exciting applications of isoprenoids, research on isoprenoid-specific bioprocesses has mostly been, and still is, limited to small-scale proof-of-concept approaches. This review presents and categorizes different ISPR solutions for biotechnological isoprenoid production and also addresses the main challenges en route towards industrial application.

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Bioprocessing for biofuels

Cited by 77 publications

References 63 publications

Structure of a PL17 Family Alginate Lyase Demonstrates Functional Similarities among Exotype Depolymerases

Structure of a PL17 Family Alginate Lyase Demonstrates Functional Similarities among Exotype Depolymerases

Photobioreactors for Sustainable Buildings

Bioprocess Engineering for Microbial Synthesis and Conversion of Isoprenoids

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