Bioprocessing of Plant-Derived Bioactive Phenolic Compounds

Holland, Brendan J.; Agyei, Dominic; Akanbi, Taiwo O.; Wang, Bo; Barrow, Colin J.

doi:10.1016/b978-0-12-811372-1.00005-1

Cited by 4 publications

(2 citation statements)

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“…These bioactive compounds characterized by therapeutic applications against various human diseases such as inflammation, cardiovascular disease, diabetic mellitus, hypertension, and oxidative stress [6] . Therefore, they must be safely and efficiently extracted from their plant sources using either organic or inorganic solvents, noting that it was better to use water as solvent extraction instead of organic solvents [7] …”

Section: Introductionmentioning

confidence: 99%

“…[6] Therefore, they must be safely and efficiently extracted from their plant sources using either organic or inorganic solvents, noting that it was better to use water as solvent extraction instead of organic solvents. [7] Thanks to their medicinal uses, African medicinal plants are used to treat various human diseases including diabetes mellitus (DM), [8] trypanosomiases, [9] various dermatological conditions, [10] Covid-19, [11,12] neurodegenerative diseases, [1] cancer, [13] etc. Therefore, more than half of the world's population still relies on medicinal plants or herbs as a source for their primary healthcare.…”

Section: Introductionmentioning

confidence: 99%

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Phenolic Profiling, Antioxidant, and Antibacterial Activities of Selected Medicinal Plants from Tunisia

Hamrouni

Romdhane

Benmoussa

et al. 2023

Chemistry & Biodiversity

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Phytochemical screening of aqueous extract from six medicinal wild plants grown in South‐eastern of Tunisia: Atriplex halimus, Teucrium polium, Moricandia arvensis, Deverra tortuoa, Haplophyllum tuberculatum and Polygonum equisetiforme were evaluated. Both decoction and ultrasound assisted extraction were used. Antioxidant, antibacterial proprieties, and phenolic profiling, using LC‐ESI‐MS method, were assessed. Total polyphenols, flavonoids, and condensed tannins contents ranged from 7.47±0.19 to 22.25±0.49 mg GAE/g Dw, 5.47±0.06 to 7.55±0.07 mg RE/g Dw, and 0.33±0.02 to 19.43±0.64 mg TAE/g Dw, respectively. Moreover, the reducing power and DPPH tests showed that P. equisetiforme (EC50: 12.50±0.50 μg/ml; DPPH⋅+: 213.49±4.24 mg TEAC/g DW), T. polium (EC50: 25.00±1.00 μg/ml; DPPH⋅+: 181.39±9.47 mg TEAC/g DW) as well as H. tuberculatum (EC50: 56.25±0.25 μg/ml; DPPH⋅+: 177.83±5.85 mg TEAC/g DW) extracts were the most effective natural antioxidants. For anti‐bacterial activity, the ultrasonic extract of H. tuberculatum showed the highest activity against both P. aeruginosa (13.50±0.71 mm) and S. aureus (13.00±0.00 mm) at 10 mg/ml. Furthermore 24 phenolic compounds were identified, with predominance of quinic acid, gallic acid, protocatechuic acid, syringic acid, p‐coumaric acid, trans‐ferulic acid, catechin (+), trans‐cinnamic and silymarin. These results were further consolidated by to heatmap clustering with P. equisetiforme, H. tuberculatum, T. polium as the main antioxidant and antibacterial sources which supports their domestication and industrial use.

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Section: Introductionmentioning

confidence: 99%