Biopsy of Minor Salivary Glands in the Diagnosis of Sarcoidosis

Orofacial presentations of sarcoidosis – a case series and review of the literature

“…7 Heerfordt's syn drome is a form of systemic sarcoidosis characterised by swelling of the parotid glands, uveitis and facial nerve palsy. 13 Involvement of the minor salivary glands in patients with sarcoidosis has been reported to range from 19-58% 14 and may help differentiate sarcoidosis from Sjögren's syndrome. 15 of the cases described in this series the diagnosis of oral sarcoidosis preceded the need for systemic treatment for pul monary involvement by fi ve years.…”

Parotid gland involvement as initial symptom in a patient with sarcoidosis

“…[17] Tükürük bezi tutulumu olunca akla ilk gelen hastal›klardan biri de Sjögren sendromudur. [18] Bizim hastam›zda da oldu¤u gibi a¤›z kurulu¤u semptomu olan hastalarda, her ne kadar ek olarak göz kurulu¤u bulunmasa da Sjögren sendromu düflünülmelidir. [19] O yüzden ay›r›m› çok iyi yapmak gerekir.…”

Orofacial Sarcoidosis and Granulomatosis

“…Several studies have shown sarcoid infiltration of the minor salivary glands with or without clinical involvement of the major salivary glands. Therefore, when accessible and clinically involved tissues are not available, the clinician can perform a biopsy of normal-appearing tissue to confirm the histologic diagnosis in a patient with compatible clinical findings (Hughes & Gross, 1972;Tarpley et al,1972;Rasmussen & Neukirch, 1976;Nessan & Jacoway, 1979).…”