Biopsy Related Prostate Status Does Not Affect on the Clinicopathological Outcome of Robotic Assisted Laparoscopic Radical Prostatectomy

Interval from Prostate Biopsy to Radical Prostatectomy Does Not Affect Immediate Operative Outcomes for Open or Minimally Invasive Approach

“…Another study used intervals of ≤2 weeks, >2 to ≤4 weeks, >4 to ≤6 weeks, >6 to ≤8 weeks, and >8 weeks with a cohort of 237 robot-assisted laparoscopic radical prostatectomies, and revealed that biopsy-to-surgery interval was not significantly associated with positive surgical margin status, operative time, and estimated blood loss ( 9 ). However, our findings are in disagreement with the results of Choi et al, who found a strong trend that robot-assisted laparoscopic radical prostatectomy performed within 4 weeks of biopsy was associates with a longer operative time (232.6 vs. 208.8 min, P =0.07) ( 8 ).…”

“…We recorded demographic and clinicopathologic variables and compared these variables between subgroups of biopsy-to-surgery interval <4 weeks and ≥4 weeks for each group. To assess the immediate operative outcome, we set the primary endpoint as positive surgical margin status and the secondary endpoints as operative time and estimated blood loss, as in most of the previous studies ( 4 , 5 , 6 , 7 , 8 , 9 ).…”

“…Traditionally, urologists tend to recommend an interval of at least 4 weeks after prostate biopsy before radical prostatectomy to allow biopsy-induced inflammation or hematoma to subside ( 3 ). However, studies have shown that early radical prostatectomy does not affect immediate operative outcomes such as operative time, estimated blood loss, and positive surgical margin status for either conventional radical retropubic prostatectomy ( 4 , 5 , 6 ) or robot-assisted laparoscopic radical prostatectomy ( 7 , 8 , 9 ). Nonetheless, to our knowledge there are no studies evaluating this subject with respect to the surgical approach.…”

A Multidimensional Analysis of Prostate Surgery Costs in the United States: Robotic-Assisted versus Retropubic Radical Prostatectomy

“…Chatterjee et al [89] have calculated opportunity costs for radical prostatectomy at $22 for each minute one approach takes using the operating room longer than another approach. This could add $330 for each RALP case based on a 15-minute robotic set-up time [90,91].…”

Short interval of biopsy to robotic-assisted laparoscopic radical prostatectomy does not render any adverse effects on the perioperative outcomes

“…[ 7 , 9 , 10 ] Meanwhile, urologist also considered that both the core numbers and the approaches of biopsy may affect the outcomes of RP. [ 11 , 12 ] It was widely agreed that sextant biopsy is inadequate and 10 to 14 cores were suggested for improving the detection of prostate cancer [ 13 ] which resulted in an increasing of biopsy core numbers in the past decades. Although the short term complications from biopsy were similar, it was still unclear that whether an extend biopsy core number would result in worse surgical outcomes of RALP when compared to conventional sextant biopsies.…”