BioRadioTransmitter: A Self-Powered Wireless Glucose-Sensing System

Hanashi, Takuya; Yamazaki, Tomohiko; Tsugawa, Wakako; Ikebukuro, Kazunori; Sode, Koji

doi:10.1177/193229681100500502

Cited by 52 publications

(48 citation statements)

References 11 publications

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“…The minimum detectable glucose concentration in this system was ∼0.2 mM and the increase in the frequency saturated at a glucose concentration of ∼20 mM. Later, Sode and co‐workers further developed a BioRadioTransmitter 55 or BioLC‐Oscillator 54 by using a radio‐transmitter circuit instead of IRLED to monitor glucose concentration (the radio wave resonance frequency changes according to glucose concentration) and miniaturized the system by reducing the size of the BFCs (Figure 5B).…”

Section: Substrate Effectmentioning

confidence: 99%

Recent Progress on the Development of Biofuel Cells for Self‐Powered Electrochemical Biosensing and Logic Biosensing: A Review

Zhou

2015

Electroanalysis

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Biofuel cells (BFCs) based on enzymes and microorganisms have been recently received considerable attention because they are recognized as an attractive type of energy conversion technology. In addition to the research activities related to the application of BFCs as power source, we have witnessed recently a growing interest in using BFCs for self‐powered electrochemical biosensing and electrochemical logic biosensing applications. Compared with traditional biosensors, one of the most significant advantages of the BFCs‐based self‐powered electrochemical biosensors and logic biosensors is their ability to detect targets integrated with chemical‐to‐electrochemical energy transformation, thus obviating the requirement of external power sources. Following my previous review (Electroanalysis 2012, 24, 197–209), the present review summarizes, discusses and updates the most recent progress and latest advances on the design and construction of BFCs‐based self‐powered electrochemical biosensors and logic biosensors. In addition to the traditional approaches based on substrate effect, inhibition effect, blocking effect and gene regulation effect for BFCs‐based self‐powered electrochemical biosensors and logic biosensors design, some new principles including enzyme effect, co‐stabilization effect, competition effect and hybrid effect are summarized and discussed by me in details. The outlook and recommendation of future directions of BFCs‐based self‐powered electrochemical biosensors and logic biosensors are discussed in the end.

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Section: Substrate Effectmentioning

confidence: 99%

Recent Progress on the Development of Biofuel Cells for Self‐Powered Electrochemical Biosensing and Logic Biosensing: A Review

Zhou

2015

Electroanalysis

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“…It should be noted that most papers on biofuel cells do not discuss the problem of their interfacing with electronics, while being concentrated on resolving internal problems of the biofuel cells, such as current efficiency, stability, etc. Two approaches have been applied to resolve the low voltage problem: (i) assembling biofuel cells in series electrically, thus increasing the total output voltage [59,[70][71][72], and (ii) collecting produced electrical energy in capacitors / charge pumps for the burst release in short pulses [73][74][75][76]. The latter approach has already been applied for activating a wireless transmitting electronic device, however using nonimplantable enzyme-based [76,77] or microbial biofuel cells [73].…”

Section: Interfacing Implanted Biofuel Cells With Biomedical Micmentioning

confidence: 99%

“…The second approach based on electronic interface devices such as charge pumps and other forms of DC-DC convertors has already been applied for the activation of a wireless transmitting electronic device; however, using nonimplantable enzyme-based [76,77] or microbial biofuel cells [73]. The application of an interface device to increase the voltage is rather well-known [78], however it should be remembered that the voltage increase is achieved at the expense of the current consumed by the charge pump, thus putting additional demand on the current output of the biofuel cell.…”

Section: Interfacing Implanted Biofuel Cells With Biomedical Micmentioning

confidence: 99%

Implantable biofuel cells operating in vivo: Providing sustainable power for bioelectronic devices: From biofuel cells to cyborgs

Katz

2015

2015 6th International Workshop on Advances in Sensors and Interfaces (IWASI)

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Implantable devices harvesting energy from biological sources and based on electrochemical transducers are currently receiving high attention. The energy collected from the body can be utilized to activate various microelectronic devices. This article is an overview of the recent research activity in the area of enzyme-based biofuel cells implanted in biological tissue and operating in vivo. The electrical power extracted from the biological sources presents use for activating microelectronic devices for biomedical applications. While some microelectronic devices can work within a fairly broad range of electrical operating conditions, others, such as pacemakers, require precise voltage levels and voltage regulation for correct operation. Thus, certain classes of electronic devices powered by implantable energy sources will require careful attention not only to energy and power considerations, but also to voltage scaling and regulation. This requires appropriate interfacing between the energy harvesting device and the energy consuming microelectronic device. The paper focuses on the problems in the present technology as well as offers their potential solutions. Lastly, perspectives and future applications of the implanted biofuel cells are also discussed. The considered examples include a pacemaker and a wireless signal transfer system powered by implantable biofuel cell extracting electrical energy from biological sources.

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“…45 The microneedle arrays were fabricated by following the methods reported by Trzebinski et al 46 The authors reported a closed loop system comprising a CGM sensor and an insulin pump interfaced via suitable control software for management of type 1 diabetes mellitus. The functionalization of working electrodes with glucose dehydrogenase was carried out by following the methods reported by Hanishi et al and Yamashita et al 47,48 The Direct electron transfer (DET) allows the operation of the electrochemical sensor at lower potentials to minimize the effect of interference from acetaminophen, ascorbic acid and uric acid. The design of the microprobe array electrodes is such that the arrays are partitioned into working, reference and background compensation electrodes to enable parallel measurements of glucose and the background currents, respectively.…”

Section: Min For 3 H With a Commercial Glucose Meter Used As Controlmentioning

confidence: 99%

Editors' Choice—Review—In Vivo and In Vitro Microneedle Based Enzymatic and Non-Enzymatic Continuous Glucose Monitoring Biosensors

Chinnadayyala

Park

Cho

2018

ECS J. Solid State Sci. Technol.

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Microneedles have emerged for transdermal monitoring of biomarkers, which are a miniaturized replica of hypodermic needles with length-scales of hundreds of micrometers, with a goal to achieve time-sensitive clinical information for routine point-of-care health monitoring. Transdermal biosensing via microneedles offers remarkable opportunities for moving biosensing technologies from research laboratories to real-field applications and enables development of easy-to-use point-of-care microdevices, minimally invasive, and with minimal-training features that are very attractive for both developed and emerging countries. This would eliminate the need for blood extraction using hypodermic needles and in turn, reduce the related problems such as infections in the patients, sample contaminations, and analysis artifacts. In this review, we provide a general overview of recent progress in microneedlebased sensing research, including: (a) in-vivo microneedle diagnostic systems for glucose monitoring with an emphasis on sensor construction and general health monitoring (b) in-vitro use of microneedle sensors. The main objective of the review is to provide a thorough and critical analysis of recent advances and developments in microneedle research field and to bridge the gap between microneedles and biosensors.

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BioRadioTransmitter: A Self-Powered Wireless Glucose-Sensing System

Cited by 52 publications

References 11 publications

Recent Progress on the Development of Biofuel Cells for Self‐Powered Electrochemical Biosensing and Logic Biosensing: A Review

Recent Progress on the Development of Biofuel Cells for Self‐Powered Electrochemical Biosensing and Logic Biosensing: A Review

Implantable biofuel cells operating in vivo: Providing sustainable power for bioelectronic devices: From biofuel cells to cyborgs

Editors' Choice—Review—In Vivo and In Vitro Microneedle Based Enzymatic and Non-Enzymatic Continuous Glucose Monitoring Biosensors

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