Bioreduction of Acetophenone Derivatives by Red Marine Algae Bostrychia radicans and B. tenella, and Marine Bacteria Associated

Abstract

The biocatalytic reduction of acetophenone derivatives was exploited by using algal biomass from Bostrychia radicans and B. tenella producing exclusively (S)-2-phenylethanols with high enantiomeric excess (> 99% ee). Bacterial populations associated with algal biomass were identified as the Bacillus genus. This report deals with the first investigations involving the use of marine bacteria associated with B. radicans and B. tenella marine algae for the biocatalytic reduction of acetophenone derivatives.

Immobilization of marine fungi on silica gel, silica xerogel and chitosan for biocatalytic reduction of ketones

“…Recently we have investigated the use of filamentous fungi from marine environments for the reduction of prochiral ketones [20,26]. Due to the excellent results obtained in the biocatalytic reduction of ketones with free cells, in this study we investigated the immobilization of living mycelia of marine fungi on various support matrices.…”

Bioreduction of fluoroacetophenone derivatives by endophytic fungi isolated from the marine red alga Bostrychia radicans

“…Spectroscopic data of the alcohols 1a-3a were compared with the literature [27]. [25,26]. Voucher specimens were deposited at the Seção de Ficologia, Instituto de Botânica de São Paulo (Herbarium SP), Brazil, under registration number SP 365678.…”

“…Among the seaweeds, the Bostrychia radicans (Montagne) Montagne is a red alga belonging to the Rhodomelaceae (order Ceramiales) family, widely disseminated in tropical and warm temperate environments [23,24]. In previous studies developed in our research group, the B. radicans alga and its isolated bacteria was used as catalyst for acetophenone derivatives bioreduction, leading to chiral alcohols with great enantioselectivity rates [25,26]. These results opened the way for a new study, involving the isolated fungi from B. radicans alga, identified as Botryosphaeria sp.…”

Multiple Monohydroxylation Products from rac-Camphor by Marine Fungus Botryosphaeria sp. Isolated from Marine Alga Bostrychia radicans

“…CBMAI 1197 was isolated from red marine alga Bostrychia radicans. 11 Therefore, different hydroxylated compounds were produced by fungal bioconversion of monoterpene.…”