Bioremediation role of Spirulina platensis against deltamethrin-mediated toxicity and its chemical residues in chicken meat

Ibrahim, Samar S; Elsabagh, Rasha; Allam, A. M.; Youssef, Gehan; Fadl, Sabreen E.; Abdelhiee, Ehab Yahya; Alkafafy, Mohamed; Soliman, Ahmed; Aboubakr, Mohamed

doi:10.1007/s11356-021-14617-8

Cited by 16 publications

(12 citation statements)

References 53 publications

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“…One-day-old, apparently healthy, Cobb broiler chicks were purchased from the El-Wataniya Poultry Company (Egypt). Chicks were divided into four experimental groups; each was performed into three replicates of five chicks: The first group (control) received a basal diet without any treatments; The second group (NAC) fed on a diet supplemented with NAC, 5.2 g/kg diet [ 21 ]; The third group (DLM) fed on a diet contaminated with DLM 300 mg/kg diet [ 22 ]; The fourth group (DLM+NAC) fed on a diet mixed with DLM and NAC, at the same rates of the above-mentioned doses. …”

Section: Methodsmentioning

confidence: 99%

N-Acetylcysteine Alleviated the Deltamethrin-Induced Oxidative Cascade and Apoptosis in Liver and Kidney Tissues

Allam

Abdeen

Devkota

et al. 2022

IJERPH

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Deltamethrin (DLM) is a synthetic pyrethroid with anti-acaricide and insecticidal properties. It is commonly used in agriculture and veterinary medicine. Humans and animals are exposed to DLM through the ingestion of polluted food and water, resulting in severe health issues. N-acetylcysteine (NAC) is a prodrug of L-cysteine, the precursor to glutathione. It can restore the oxidant-antioxidant balance. Therefore, this research aimed to examine whether NAC may protect broiler chickens against oxidative stress, at the level of biochemical and molecular alterations caused by DLM intoxication. The indicators of liver and kidney injury in the serum of DLM-intoxicated and NAC-treated groups were examined. Furthermore, lipid peroxidation, antioxidant markers, superoxide dismutase activity, and apoptotic gene expressions (caspase-3 and Bcl-2) were investigated. All parameters were significantly altered in the DLM-intoxicated group, suggesting that DLM could induce oxidative damage and apoptosis in hepato-renal tissue. The majority of the changes in the studied parameters were reversed when NAC therapy was used. In conclusion, by virtue of its antioxidant and antiapoptotic properties, NAC enabled the provision of significant protection effects against DLM-induced hepato-renal injury.

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Section: Methodsmentioning

confidence: 99%

N-Acetylcysteine Alleviated the Deltamethrin-Induced Oxidative Cascade and Apoptosis in Liver and Kidney Tissues

Allam

Abdeen

Devkota

et al. 2022

IJERPH

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“…Regarding the contents of protein and fat, the data vary across different Spirulina intake levels. For instance, at a 2.0% feed level (65.4 g/bird), Ibrahim et al [ 10 ] reported an increase in protein content. However, other studies, like those by Bonos et al [ 3 ] at 0.50% and 1.0% feed levels (21.5 and 41.3 g/bird), did not show significant changes in protein and fat contents.…”

Section: Influence Of Cumulative Spirulina Intake On Broiler Meat Nut...mentioning

confidence: 99%

“…For instance, a maize- and soybean-based diet was used by El-Bahr et al [ 4 ], Pestana et al [ 9 ], Ibrahim et al [ 10 ] and Mullinex et al [ 21 ], whereas maize and barley and maize, soybean and wheat were the basal ingredients applied by Toyomizu et al [ 18 ] and Altmann et al [ 11 ], Park et al [ 8 ] and Altmann et al [ 24 ], respectively. Moreover, the differences observed in the nutritional composition of broiler meat, particularly in terms of lipids and protein, can be attributed to the bioaccessibility and digestibility of Spirulina nutrients and not just to the composition of basal diets fed to broilers, which were similar between studies [ 10 , 11 , 24 ]. The bioaccessibility of Spirulina nutrients can be enhanced through the application of mechanical or enzymatic pre-treatments [ 29 , 30 ].…”

Section: Influence Of Cumulative Spirulina Intake On Broiler Meat Nut...mentioning

confidence: 99%

“…These components not only enhance the growth performance of broilers but also positively impact meat quality [ 5 ]. Studies have shown that Spirulina inclusion can modify meat colour, an attribute largely influenced by its carotenoid content, leading to enhanced consumer appeal [ 10 ]. Moreover, the impact of Spirulina on the fatty acid profile and antioxidant capacity of broiler meat has garnered significant interest.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Cumulative Spirulina Intake on Broiler Meat Quality, Nutritional and Health-Related Attributes

Spínola,

Costa,

Prates

2024

Foods

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This work aimed to assess how different cumulative levels of Spirulina (Arthrospira platensis) intake influence individual broiler meat quality parameters, nutritional value and health-related traits. The data analysed showed varying cumulative Spirulina intake levels, ranging from 3.46 to 521 g/bird, with large changes in meat traits. The key findings indicate that Spirulina intake significantly enhances meat colour, primarily due to its rich carotenoid content. However, this enhancement shows a saturation effect at higher intake levels, where additional Spirulina does not further improve the colour. Regarding the meat nutritional profile, Spirulina increases beneficial n − 3 polyunsaturated fatty acids and reduces lipid oxidation. These effects on meat, however, are not linear and become more complex at higher microalga intake levels. Regarding meat sensory attributes, moderate Spirulina levels positively influence flavour and texture. Still, higher levels may lead to changes not universally preferred by meat consumers, highlighting the need for balanced Spirulina inclusion in diets. Optimal Spirulina cumulative intake levels must be identified to balance meat’s nutritional benefits with consumer preferences. Additionally, ensuring Spirulina’s purity and adherence to regulatory standards is essential for consumer safety and market access. These findings provide valuable insights for poultry nutritionists and the food industry, emphasising the necessity of a balanced approach to Spirulina’s incorporation in poultry diets.

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“…Xenobiotics contain herbicides that are widely used for the production of food; however, they also represent a threat to living creatures due to their residues in air, water, vegetables, and products of animal origin. [ 1 ] Recently, environmental, occupational, and dietary exposure to herbicides [ 2 ] and insecticides [ 3,4 ] caused several health problems in humans and animals. Glyphosate (GLP), N ‐phosphonomethyl‐glycine, is one of the most commonly used broad‐spectrum herbicides [ 5 ] and is effective in the removal of undesirable weeds.…”

Section: Introductionmentioning

confidence: 99%

Ameliorative effect of N‐acetylcysteine on the testicular tissue of adult male albino rats after glyphosate‐based herbicide exposure

Hashim

Bashir

Yasin

et al. 2022

J Biochem & Molecular Tox

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Glyphosate (GLP) is a broad-spectrum herbicide that is frequently used in crop production, but its residues remain in foodstuffs. This, in turn, has led to potential adverse effects on both human and animal health. Recent studies emphasized that GLP induces teratogenic effects and reproductive disorders, but its mechanism of toxicity is highly debated. N-acetylcysteine (NAC) is well known for its potent antioxidant capacity in addition to anti-inflammatory and cytoprotective properties.Therefore, our study aimed to investigate the reproductive toxicity of GLP in mature rats and evaluate the possible ameliorative effect of NAC against this toxicity. To this end, 30 adult male rats were assigned into three groups (10 rats per group) as follows: Group I, negative control; group II, GLP-exposed; 375 mg/kg GLP, orally; group III, NAC-cotreated, 160 mg/kg NAC 1 h before GLP, plus GLP, 375 mg/kg orally for 6 weeks. At the end of the experiment, the testicles were collected for semen analysis and biochemical, histopathological, and immunohistochemical studies. GLP-exposed rats exhibited disturbances in seminal parameters and a significant increase in malondialdehyde levels and expression of apoptotic markers. Several histopathological changes were observed, including strong immunoreactions for caspase-3 and proliferating cell nuclear antigen. Conversely, the administration of NAC before GLP was able to improve seminal parameters, attenuate the induced oxidative stress and apoptosis in addition to the regeneration of testicular damage.In conclusion, NAC can ameliorate the reproductive toxicity induced by GLP to an acceptable degree.

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Bioremediation role of Spirulina platensis against deltamethrin-mediated toxicity and its chemical residues in chicken meat

Cited by 16 publications

References 53 publications

N-Acetylcysteine Alleviated the Deltamethrin-Induced Oxidative Cascade and Apoptosis in Liver and Kidney Tissues

N-Acetylcysteine Alleviated the Deltamethrin-Induced Oxidative Cascade and Apoptosis in Liver and Kidney Tissues

Effect of Cumulative Spirulina Intake on Broiler Meat Quality, Nutritional and Health-Related Attributes

Ameliorative effect of N‐acetylcysteine on the testicular tissue of adult male albino rats after glyphosate‐based herbicide exposure

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