Biosafety chemistry and biosafety materials: A new perspective to solve biosafety problems

Abstract

The Novel Coronavirus Disease (COVID-19) has rapidly swept around the globe since its first emergence near 2020. However, people have failed to fully understand its origin or mutation. Defined as an international biosafety incident, COVID-19 has again encouraged worldwide attention to reconsider the importance of biosafety due to the adverse impact on personal well-being and social stability. Most countries have already taken measures to advocate progress in biosafety-relevant research, aiming to prevent and solve biosafety problems with more advanced techniques and products. Herein, we propose a new concept of biosafety chemistry and reiterate the notion of biosafety materials, which refer to the interdisciplinary integration of biosafety and chemistry or materials. Here, we attempt to illustrate the exquisite association that chemistry and material science possess with biosafety fields and we hope to provide a pragmatic perspective on approaches to utilize the knowledge of these two subjects to handle specific biosafety issues such as detection and disinfection of pathogenic microorganisms, personal and collective protective equipment, vaccine adjuvants and specific drugs, preservation of biogenetic resources for human, animals, and plants. In addition, we hope to convey and promote the idea of multidisciplinary cooperation to strengthen biosafety research and development of relevant products for establishing possibly specific majors to defend national security in the future.

Nanosystems for Immune Regulation against Bacterial Infections: A Review

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a wake-up call to develop more biosafety systems against the infection of microorganisms including viruses, fungi, and bacteria. , The utilization of nanosystems to mediate the immune system is a promising method to combat bacterial infection and bacterial AMR. Nanosystems can serve as vaccines to prevent bacterial infections in the host.…”

Combination of chemistry and material science to overcome health problems

“…In this context, Wu and Xiao have proposed the development of a new field termed biosafety chemistry and biosafety materials. [11] , [12] This field of research could become a new discipline within the chemical sciences and could present novel solutions exemplary for the rapid and early detection of new pathogens, the disinfection of surfaces, the preparation of protective equipment, or the treatment of patients with antimicrobial (bacterial, fungal, viral, parasitic) drug formulations. Importantly, this field of research requires expertise from various types of natural science including molecular chemistry, biology, and material science, and therefore presents a multidisciplinary discipline with influences from various resources.…”

Epicatechin-assembled nanoparticles against renal ischemia/reperfusion injury

“…28,29 It should be noted that small polyphenol molecules have good antioxidant effects in a variety of inflammatory diseases, while their main potential risks include stability, application sustainability, and safety. [30][31][32][33] Typically, the development of suitable material chemistry methods to integrate small molecular polyphenols into macromolecular nanomaterials is an effective strategy, 34 and some methods have been successful in many types of polyphenols, such as grape seed polyphenols, 35 tea polyphenols, 36 and curcumin. 37 Considering the rich molecular library of polyphenols, it would be interesting to explore polyphenolic-based biomaterials for inflammatory diseases.…”