Biosensing by Densely Packed and Optically Coupled Plasmonic Particle Arrays

Sannomiya, Takumi; Sahoo, Pratap K.; Mahcicek, Davut I.; Solak, Harun H.; Hafner, Christian; Grieshaber, Dorothee; Vörös, János

doi:10.1002/smll.200900284

Cited by 55 publications

(49 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These LSPRs can be resonantly excited, and are very sensitive to the refractive index of the dielectric medium (Stewart et al, 2008; Sepulveda et al, 2009). Detection limits in pg/cm 2 for different proteins have been achieved with these plasmonic sensors (Chen et al, 2009; Sannomiya et al, 2009). However, the low probe penetration depth and limited shelf life of the nanoplasmonic sensors restrain their application in detecting a wide range of analytes (Kabashin et al, 2009; Anker et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Silicon photonic crystal nanocavity-coupled waveguides for error-corrected optical biosensing

Pal

Guillermain

Sriram

et al. 2011

Biosensors and Bioelectronics

107

View full text Add to dashboard Cite

A photonic crystal (PhC) waveguide based optical biosensor capable of label-free and error-corrected sensing was investigated in this study. The detection principle of the biosensor involved shifts in the resonant mode wavelength of nanocavities coupled to the silicon PhC waveguide due to changes in ambient refractive index. The optical characteristics of the nanocavity structure were predicted by FDTD theoretical methods. The device was fabricated using standard nanolithography and reactive-ion-etching techniques. Experimental results showed that the structure had a refractive index sensitivity of 10−2 RIU. The biosensing capability of the nanocavity sensor was tested by detecting human IgG molecules. The device sensitivity was found to be 2.3 ± 0.24 × 105 nm/M with an achievable lowest detection limit of 1.5 fg for human IgG molecules. Additionally, experimental results demonstrated that the PhC devices were specific in IgG detection and provided concentration-dependent responses consistent with Langmuir behavior. The PhC devices manifest outstanding potential as microscale label-free error-correcting sensors, and may have future utility as ultrasensitive multiplex devices.

show abstract

Section: Introductionmentioning

confidence: 99%

Silicon photonic crystal nanocavity-coupled waveguides for error-corrected optical biosensing

Pal

Guillermain

Sriram

et al. 2011

Biosensors and Bioelectronics

107

View full text Add to dashboard Cite

show abstract

“…4b). Interestingly, this LSP decay length is longer than that observed from single nanoparticles or nanoparticles in an array (< 30 nm) 22, 23…”

mentioning

confidence: 66%

Enhanced Optical Transmission Mediated by Localized Plasmons in Anisotropic, Three-Dimensional Nanohole Arrays

Yang¹,

Gao²,

Suh³

et al. 2010

Nano Lett.

View full text Add to dashboard Cite

This paper describes 3D nanohole arrays whose high optical transmission is mediated more by localized surface plasmon (LSP) excitations than by surface plasmon polaritons (SPPs). First, LSPs on 3D hole arrays lead to optical transmission an order of magnitude higher than 2D planar hole arrays. Second, LSP-mediated transmission is broadband and more tunable than SPPenhanced transmission which is restricted by Bragg coupling. Third, for the first time, two types of surface plasmons can be selectively excited and manipulated on the same plasmonic substrate. This new plasmonic substrate fabricated by high-throughput nanolithography techniques paves the way for cutting-edge optoelectronic and biomedical applications.Keywords nanohole array; enhanced optical transmission; plasmonics; molding; surface plasmon polariton; localized surface plasmon Surface plasmon polaritons (SPPs) mediate light-matter interactions in subwavelength hole arrays and are the dominant mechanism for enhanced optical transmission,1 , 2 plasmonic focusing,3 and the plasmon Talbot effect.4 , 5 Most work to date has focused on manipulating SPPs by tuning the hole shape,6 , 7 the array symmetry,8 , 9 or the superlattice geometry.10 , 11 However, the tailoring of only the in-plane, two-dimensional (2D) structure has limited the excitation of strong localized surface plasmons (LSPs) within individual holes. Here we report that LSPs from three-dimensional (3D) nanoholes enhance transmission more than SPPs from the same nanohole array. Subwavelength hole arrays with anisotropic hole shapes were fabricated by metal deposition at oblique angles on nanopyramidal templates. Localized resonances supported by 3D holes produced broadband optical transmission with intensities an order of magnitude higher than that from 2D planar nanohole arrays. Moreover, in contrast to SPP-mediated enhanced transmission,12 , 13 LSPenhanced optical transmission at different wavelengths and with different dispersion properties can be tuned by controlling the shape of the 3D hole. The discovery of broadband-tunable LSP and SPP resonances on the same plasmonic substrate provides new opportunities in optoelectronics and optical biosensing.* To whom correspondence should be addressed. todom@northwestern.edu. Figure 1 summarizes how metal films perforated with 3D nanoholes were fabricated from templates of nanopyramidal pits followed by metal deposition at oblique angles. Protruding 3D nanohole arrays (tapered ends pointing away from the substrate) were fabricated by deposition of gold (Au) at specific angles (α) on a silicon (Si) template followed by template-stripping14 using UV-curable polyurethane (PU) as the transfer material (Fig. 1a). PU replicas of the Si template were formed by first molding poly(dimethylsiloxane) (PDMS) against the Si nanopatterns and then molding the patterned PDMS against PU (Fig. 1b). Recessed 3D hole arrays (tapered ends pointing toward the substrate) were generated by the angled deposition of Au directly on the PU template (Fig. 1b). For bot...

show abstract

“…The correlation between the plasmon peak position and the bulk RI sensitivity has been verified experimentally by several groups including ours. [147][148][149] In Paper IV, the RI sensitivity was investigated for a large variety of gold nanoparticles with different plasmon frequencies, obtaining a clearly linear relationship between the plasmon peak resonance position and the bulk RI sensitivity ( Figure 5.4). However, it is important to notice that this correlation only is valid for dispersed nanoparticles in solution.…”

Section: Refractive Index Sensitivitymentioning

confidence: 99%

Nanoplasmonic Sensing using Metal Nanoparticles

Martinsson¹

2014

View full text Add to dashboard Cite

In our modern society, we are surrounded by numerous sensors, constantly feeding us information about our physical environment. From small, wearable sensors that monitor our physiological status to large satellites orbiting around the earth, detecting global changes. Although, the performance of these sensors have been significantly improved during the last decades there is still a demand for faster and more reliable sensing systems with improved sensitivity and selectivity. The rapid progress in nanofabrication techniques has made a profound impact for the development of small, novel sensors that enables miniaturization and integration. A specific area where nanostructures are especially attractive is biochemical sensing, where the exceptional properties of nanomaterials can be utilized in order to detect and analyze biomolecular interactions.The focus of this thesis is to investigate plasmonic nanoparticles composed of gold or silver and optimize their performance as signal transducers in optical biosensors. Metal nanoparticles exhibit unique optical properties due to excitation of localized surface plasmons, which makes them highly sensitive probes for detecting small, local changes in their surrounding environment, for instance the binding of a biomolecule to the nanoparticle surface. This is the basic principle behind nanoplasmonic sensing based on refractometric detection, a sensing scheme that offers real-time and label-free detection of molecular interactions.This thesis shows that the sensitivity for detecting local refractive index changes is highly dependent on the geometry of the metal nanoparticles, their interaction with neighboring particles and their chemical composition and functionalization. An increased knowledge about how these parameters affects the sensitivity is essential when developing nanoplasmonic sensing devices with high performance based on metal nanoparticles. VI VII Populärvetenskaplig sammanfattningI dagens samhälle finns en påtaglig vilja och strävan efter att kunna mäta, övervaka, analysera och reglera vardagliga funktioner och beteenden. Detta har lett till en explosionsartad utveckling av nya, funktionella sensorer som numera finns överallt i våra liv -i hemmet, på arbetsplatsen, i våra fickor och till och med inuti våra kroppar. En biosensor är en särskild typ av sensor som används för att detektera specifika kemiska eller biologiska ämnen genom att omvandla förekomsten av dessa ämnen till en mätbar signal. Biosensorer kan användas inom flera olika områden som livsmedelindustri, processövervakning, kriminalteknologi samt inom medicinsk diagnostik. Ofta är dock koncentrationen av de eftersökta ämnena mycket låg vilket ställer stora krav på sensorernas känslighet och precision.I denna avhandling beskrivs hur nanopartiklar av guld och silver kan användas som signalomvandlare i optiska biosensorer. Metalliska nanopartiklar har unika optiska egenskaper vilket gör dem väldigt känsliga mot små förändringar i dess absoluta närhet. Sådana förändringar ger upphov till en färgf...

show abstract

Biosensing by Densely Packed and Optically Coupled Plasmonic Particle Arrays

Cited by 55 publications

References 36 publications

Silicon photonic crystal nanocavity-coupled waveguides for error-corrected optical biosensing

Silicon photonic crystal nanocavity-coupled waveguides for error-corrected optical biosensing

Enhanced Optical Transmission Mediated by Localized Plasmons in Anisotropic, Three-Dimensional Nanohole Arrays

Nanoplasmonic Sensing using Metal Nanoparticles

Contact Info

Product

Resources

About