“…The immobilization of the enzyme can be carried out via short-chain thiol modified gold electrodes, long-chain thiol (mercaptoundecanoic acid), mixed-thiol, long-chain mixed thiol (mercaptoundecanoic acid/mercaptoundecanol) and hemin modified electrode (McNeil et al, 1995;Gobi and Mizutani, 2000;Ignatov et al, 2002). However, the performance of many of these types of devices is interfered by hydrogen peroxide, uric acid and some communication interference between the protein and the electrode (Chen et al, 2000;Beissenhirtz et al, 2004;Endo et al, 2002;Campanella et al, 2004;Emregül, 2005). The protective effect of antioxidants at a cellular level could only be achieved by monitoring the DNA integrity (Barroso et al, 2011).…”