Biosensors for healthcare: current and future perspectives

Kim, Eun Ryung; Joe, Cheulmin; Mitchell, Robert J.; Gu, Man Bock

doi:10.1016/j.tibtech.2022.12.005

Cited by 74 publications

(28 citation statements)

References 150 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Biomolecule Monitoringmentioning

confidence: 99%

“…Biosensors facilitating the examination of biomolecules across diverse samples constitute essential instruments for endeavors in analytical and biochemical research, alongside their crucial roles in medical diagnostics for human healthcare. 26 In this regard, metaphotonic metasurfaces have emerged as a potent foundation for biomolecular sensing technologies. 27 Dielectric metasurfaces with a high quality (Q) factor in the BIC mode have been employed in hyperspectral imaging techniques to achieve highly sensitive biomolecule detection.…”

Section: ■ Biomolecule Monitoringmentioning

confidence: 99%

See 1 more Smart Citation

Metasurfaces for Quantitative Biosciences of Molecules, Cells, and Tissues: Sensing and Diagnostics

Barulin,

Nguyen,

Kim

et al. 2024

ACS Photonics

View full text Add to dashboard Cite

Metasurfaces have revolutionized optical biosensing and diagnostic assays due to their sensitivity, compactness, and label-free operation. However, metasurface applications in analyzing complex biological systems and quantum bioscience phenomena remain scarce. In this Perspective, we discuss current developments in metasurface biosensors and propose promising future applications for probing or adopting quantum bioscience effects and improving spatial omics analysis in live cells and tissues. We discuss the capabilities of the current metasurface platforms for monitoring relevant biomarkers of viral diseases, neurodegenerative diseases, and cancers. Metasurfaceempowered examination of cell morphology and secretome, virus detection, and tissue imaging can improve the accuracy of early diagnosis. Furthermore, we review device-integration approaches for point-of-care testing settings that could constitute pathways toward technology commercialization. Altogether, we provide a perspective for exploring metasurface applications in precision health and medicine.

show abstract

Section: Biomolecule Monitoringmentioning

confidence: 99%

Section: ■ Biomolecule Monitoringmentioning

confidence: 99%

Metasurfaces for Quantitative Biosciences of Molecules, Cells, and Tissues: Sensing and Diagnostics

Barulin,

Nguyen,

Kim

et al. 2024

ACS Photonics

View full text Add to dashboard Cite

show abstract

“…(Suo et al, 2023) and LFAs are restricted to 1D horizontal fluidic flow. However, µPADs create channels through which fluids can flow in multiple directions without the use of additional elements by using patterned surfaces (Kim et al, 2023). By defining channel networks in a porous paper in two or three dimensions, fluid control is improved and more complex assays can be implemented in µPADs (Ordutowski et al, 2023).…”

Section: Market Demand and Future Prospectsmentioning

confidence: 99%

Evaluation of food μPADs with the new tech perspectives and future prospects

Okutan Arslan,

Trabzon

2023

eFood

View full text Add to dashboard Cite

Food microfluidic paper‐based analytical devices (µPADs) are powerful tools to create total analysis systems and have long been demonstrated to be useful for safety and quality applications. Thanks to new technological innovations food µPADs offer exciting new possibilities. This review introduces how µPADs are obtained from chromatography, filter, or office papers and detect analytes from a food sample. We introduce the most current developments in the use of µPADs with an emphasis on paper types, adapted new technologies, and detection limits. Classifications are also made on food µPADs according to applied innovations and adapted novel technologies. In the first section, simple forms of µPADs for the detection of pathogen, mycotoxin, pesticides, and other food components are discussed with technical details. Then, we introduce multisensing approaches for high throughput analysis and a concise summary will be given. In the case of three‐dimensional (3D) µPADs, the use of 3D is discussed and compared to 2D µPADs in terms of its advantageous with the example of a food colorant test device. In the following section, smartphone adoption to µPADs is introduced in detail with eight different assay examples. Centrifugal platform for nickel assay is demonstrated as an enabling approach with shortened assay times by rotational velocity. The potential of user‐friendly hybrid devices is also summarized in the last part. Finally, we present an outlook to underline the opportunities created by smartphone‐based and intelligent µPADs for food safety and quality with real success perspectives

show abstract

“…[4][5][6] The presence of the residue of MTL in environmental water bodies could have a serious impact on human health, such as sore eyes, skin damage, heart-related diseases, nausea, and damage to the internal organs. 7,8 Some countries control the presence of organic residues from the photographic industry in environmental samples. 9 Therefore, it is salient to examine the lower detection limit of MTL.…”

Section: Introductionmentioning

confidence: 99%