Biosynthesis of poly(3-hydroxybutyrate) and its copolymers by Yangia sp. ND199 from different carbon sources

Phong, Tran Huu; Thược, Đoàn Văn; Sudesh, Kumar

doi:10.1016/j.ijbiomac.2015.12.037

Cited by 15 publications

(7 citation statements)

References 22 publications

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“…In this study, increasing the salt concentration to 5% (w/v) was even found to be favorable for the production of EPS. The salt concentration was not increased further since the earlier studies indicated a decrease in both cell growth and PHA levels at a higher salt concentration (Phong et al, 2016; Van‐Thuoc et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…The PHA and EPS concentrations were determined once after 48 h based on previous reports on Yangia sp. ND199 (Phong et al, 2016).…”

Section: Methodsmentioning

confidence: 99%

“…Unless specified, the carbon source used is glucose, the nitrogen source is yeast extract, and the concentration of phosphate salts in the medium (1x) is equivalent to 30 mM. (Dai et al, 2006;Lau et al, 2017;Phong et al, 2016;van-Thuoc et al, 2012van-Thuoc et al, , 2015.…”

Section: Eps Compositionmentioning

confidence: 99%

“…Subsequently, Yangia sp. ND199, isolated from mangroves in the Nam Dinh province in northern Vietnam, was shown to produce the copolymer P(3HB‐ co ‐3HV) from structurally unrelated carbon sources (Phong et al, 2016; Van‐Thuoc et al, 2012, 2015), a characteristic similar to Hfx. mediterranei (Han et al, 2010), but uncommon among bacterial species.…”

Section: Introductionmentioning

confidence: 99%

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Metabolic potential of the moderate halophile Yangia sp. ND199 for co‐production of polyhydroxyalkanoates and exopolysaccharides

et al. 2021

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Yangia sp. ND199 is a moderately halophilic bacterium isolated from mangrove samples in Northern Vietnam, which was earlier reported to grow on several sugars and glycerol to accumulate poly(hydroxyalkanoates) (PHA). In this study, the potential of the bacterium for co‐production of exopolysaccharides (EPS) and PHA was investigated. Genome sequence analysis of the closely related Yangia sp. CCB‐M3 isolated from mangroves in Malaysia revealed genes encoding enzymes participating in different EPS biosynthetic pathways. The effects of various cultivation parameters on the production of EPS and PHA were studied. The highest level of EPS (288 mg/L) was achieved using sucrose and yeast extract with 5% NaCl and 120 mM phosphate salts but with modest PHA accumulation (32% of cell dry weight, 1.3 g/L). Growth on fructose yielded the highest PHA concentration (85% of CDW, 3.3 g/L) at 90 mM phosphate and higher molecular weight EPS at 251 mg/L yield at 120 mM phosphate concentration. Analysis of EPS showed a predominance of glucose, followed by fructose and galactose, and minor amounts of acidic sugars.

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Section: Discussionmentioning

confidence: 99%

“…The PHA and EPS concentrations were determined once after 48 h based on previous reports on Yangia sp. ND199 (Phong et al, 2016).…”

Section: Methodsmentioning

confidence: 99%

Section: Eps Compositionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Metabolic potential of the moderate halophile Yangia sp. ND199 for co‐production of polyhydroxyalkanoates and exopolysaccharides

et al. 2021

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“…Although PHB is the most widely studied and most promising PHA member, its practical applications have been greatly hindered due to unfavorable low elongation fracture or high crystallinity. Recent endeavors show that the formation of copolymers by the introduction of carefully designed co‐monomers can significantly improve the chemical and physical performances of PHB …”

Section: Synthesis Of Polyhydroxyalkanoatesmentioning

confidence: 99%

Recent Progress in Polyhydroxyalkanoates‐Based Copolymers for Biomedical Applications

Luo

Liu

et al. 2019

Biotechnology Journal

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In recent years, naturally biodegradable polyhydroxyalkanoate (PHA) monopolymers have become focus of public attentions due to their good biocompatibility. However, due to its poor mechanical properties, high production costs, and limited functionality, its applications in materials, energy, and biomedical applications are greatly limited. In recent years, researchers have found that PHA copolymers have better thermal properties, mechanical processability, and physicochemical properties relative to their homopolymers. This review summarizes the synthesis of PHA copolymers by the latest biosynthetic and chemical modification methods. The modified PHA copolymer could greatly reduce the production cost with elevated mechanical or physicochemical properties, which can further meet the practical needs of various fields. This review further summarizes the broad applications of modified PHA copolymers in biomedical applications, which might shred lights on their commercial applications.

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Genome Mining Reveals the Biosynthetic Pathways of Polyhydroxyalkanoate and Ectoines of the Halophilic Strain Salinivibrio proteolyticus M318 Isolated from Fermented Shrimp Paste

et al. 2020

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Biosynthesis of poly(3-hydroxybutyrate) and its copolymers by Yangia sp. ND199 from different carbon sources

Cited by 15 publications

References 22 publications

Metabolic potential of the moderate halophile Yangia sp. ND199 for co‐production of polyhydroxyalkanoates and exopolysaccharides

Metabolic potential of the moderate halophile Yangia sp. ND199 for co‐production of polyhydroxyalkanoates and exopolysaccharides

Recent Progress in Polyhydroxyalkanoates‐Based Copolymers for Biomedical Applications

Genome Mining Reveals the Biosynthetic Pathways of Polyhydroxyalkanoate and Ectoines of the Halophilic Strain Salinivibrio proteolyticus M318 Isolated from Fermented Shrimp Paste

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