Biosynthesis of silver nanoparticles (Ag-NPs) using Senna alexandrina grown in Saudi Arabia and their bioactivity against multidrug-resistant pathogens and cancer cells

Alharbi, Naiyf S.; Khaled, Jamal M.; Alanazi, Khaled; Kadaikunnan, Shine; Alobaidi, Ahmed S.

doi:10.1016/j.jsps.2023.04.015

Cited by 8 publications

(2 citation statements)

References 39 publications

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“…Therefore, antimicrobial packaging materials can be prepared by introducing antimicrobial additives into cellulose-based materials that do not have antimicrobial activity by themselves, allowing them to be used more widely in the market. Silver nanoparticles (Ag NPs) are considered to be the most commonly used inorganic antibacterial material, which has been widely used in medicine [14], wound dressing [15], pharmaceutical [16], and other fields. Ag NPs have good antimicrobial performance and biocompatibility, which are suitable for incorporation into cellulose-based materials to prepare antimicrobial composites.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Properties of Carboxymethyl Cellulose/Starch/N’N Methylenebisacrylamide Membranes Endowed by Ultrasound and Their Potential Application in Antimicrobial Packaging

Cheng,

Fang

et al. 2024

Polymers

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Cellulose is used widely in antimicrobial packaging due to its abundance in nature, biodegradability, renewability, non-toxicity, and low cost. However, how efficiently and rapidly it imparts high antimicrobial activity to cellulose-based packaging materials remains a challenge. In this work, Ag NPs were deposited on the surface of carboxymethyl cellulose/starch/N’N Methylenebisacrylamide film using ultrasonic radiation. Morphology and structure analysis of as-prepared films were conducted, and the antibacterial effects under different ultrasonic times and reductant contents were investigated. These results showed that Ag NPs were distributed uniformly on the film surface under an ultrasonic time of 45 min. The size of Ag NPs changes as the reducing agent content decreases. The composite film demonstrated a slightly better antibacterial effect against E. coli than against S. aureus. Therefore, this work can provide valuable insights for the research on antimicrobial packaging.

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Section: Introductionmentioning

confidence: 99%

Antimicrobial Properties of Carboxymethyl Cellulose/Starch/N’N Methylenebisacrylamide Membranes Endowed by Ultrasound and Their Potential Application in Antimicrobial Packaging

Cheng,

Fang

et al. 2024

Polymers

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“…Therefore, the biocompatibility and stability of SeNPs can be enhanced by synthesizing them using biomolecules. Green manufacturing of SeNPs has gained significant interest as an alternative method because of several benefits, which include its simple, cost-effective, scalable, and eco-friendly method ( Alharbi et al, 2023 ). Several chemical reduction processes are reported for synthesizing SeNPs ( Shoeibi et al, 2017 ); however, the incorporation of biological processes, including enzymes, microorganisms, and plant extracts, referred to as green chemistry, is imperative for manufacturing SeNPs ( Pyrzynska and Sentkowska, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Facile green synthesis and characterization of Terminalia arjuna bark phenolic–selenium nanogel: a biocompatible and green nano-biomaterial for multifaceted biological applications

Puri,

Mohite,

Patil

et al. 2023

Front. Chem.

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Biogenic nanoparticle production is in demand as it is secure, has great promise, and is environmental friendly. This study aimed at green synthesis, characterization, and evaluation of Terminalia arjuna selenium nanoparticles (TA-SeNPs) for their antioxidant, antibacterial, anticancer activities, and their incorporation in gel for biomedical applications. The bio-reduction attributes of the T. arjuna (TA) bark extract were utilized to fabricate selenium nanoparticles. The TA bark extract is abundant in phenolics (193.63 ± 1.61 mg gallic acid equivalents/g), flavonoids (88.23 ± 0.39 mg quercetin equivalents/g), and tannins (109.46 ± 1.16 mg catechin equivalents/g), which perform as effective capping and stabilizing agents, thus enabling the fabrication of stable SeNPs. The fabrication of TA-SeNPs was corroborated by UV–visible spectra, which exhibited surface plasmon resonance at 291 nm. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) demonstrated nano-sized spherical TA-SeNPs with an average diameter ranging from 100 to 150 nm. Zeta potential analysis revealed that TA-SeNPs were negatively charged (−26.1 mV). X-ray diffraction presented amorphous TA-SeNPs with a quantification of 82.36 ± 10.2 μg/mL resulting from ICP-AES. The IC50 45.18 ± 0.11 μg/mL for the DPPH assay and 66.51% reducing power capacity values indicated that the TA-SeNPs possessed excellent radical scavenging efficacy. Moreover, the TA-SeNPs exhibited a broad spectrum of antimicrobial activity against potential pathogens. Additionally, the TA-SeNPs exhibited a dose-dependent cytotoxic effect on the MCF-7 breast cancer cell line, with an IC50 of 23.41 μg/mL. Furthermore, the TA-SeNP-incorporated gel showed excellent spreadability, extrudability, and consistency with retention of antimicrobial properties and hydrophilic contact angle. As an outcome, TA-SeNPs offer the possibility of the formulation and growth of sustainably designed green SeNPs that can be produced, conserved, and marketed securely across the globe.

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Organoids as an in vitro model to study human tumors and bacteria

Liu,

et al. 2024

Journal of Surgical Oncology

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Organoids faithfully replicate the morphological structure, physiological functions, stable phenotype of the source tissue. Recent research indicates that bacteria can significantly influence the initiation, advancement, and treatment of tumors. This article provides a comprehensive review of the applications of organoid technology in tumor research, the relationship between bacteria and the genesis and development of tumors, and the exploration of the impact of bacteria on tumors and their applications in research.

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Biosynthesis of silver nanoparticles (Ag-NPs) using Senna alexandrina grown in Saudi Arabia and their bioactivity against multidrug-resistant pathogens and cancer cells

Cited by 8 publications

References 39 publications

Antimicrobial Properties of Carboxymethyl Cellulose/Starch/N’N Methylenebisacrylamide Membranes Endowed by Ultrasound and Their Potential Application in Antimicrobial Packaging

Antimicrobial Properties of Carboxymethyl Cellulose/Starch/N’N Methylenebisacrylamide Membranes Endowed by Ultrasound and Their Potential Application in Antimicrobial Packaging

Facile green synthesis and characterization of Terminalia arjuna bark phenolic–selenium nanogel: a biocompatible and green nano-biomaterial for multifaceted biological applications

Organoids as an in vitro model to study human tumors and bacteria

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