1968
DOI: 10.1126/science.159.3814.498
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Biosynthesis of Surface Lipids

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Cited by 120 publications
(16 citation statements)
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“…One such possible mechanism consistent with the available evidence involves a headto-head condensation of two biochemically dissimilar derivatives of fatty acids with the specific decarboxylation of one of them (Kolattukudy, 1968d). One such possible mechanism consistent with the available evidence involves a headto-head condensation of two biochemically dissimilar derivatives of fatty acids with the specific decarboxylation of one of them (Kolattukudy, 1968d).…”
supporting
confidence: 52%
“…One such possible mechanism consistent with the available evidence involves a headto-head condensation of two biochemically dissimilar derivatives of fatty acids with the specific decarboxylation of one of them (Kolattukudy, 1968d). One such possible mechanism consistent with the available evidence involves a headto-head condensation of two biochemically dissimilar derivatives of fatty acids with the specific decarboxylation of one of them (Kolattukudy, 1968d).…”
supporting
confidence: 52%
“…The diagram is based on the elongation-decarboxylation scheme proposed by Kolattukudy (see ref. [8] ). The wax classes are divided into three groups according to the reactions occurring after the C16 or Cls fatty acid precursors have been elongated to specific lengths: 1) primary alcohols, esters and aldehydes formed via the reductive pathway; 2) hydrocarbons formed via the decarboxylative pathway, and 3) free fatty acids formed via dissociation from the elongation complex.…”
Section: Resultsmentioning
confidence: 99%
“…Widespread occurrence of hydrocarbons in animals, accumulation of hydrocarbons under pathological conditions (3,4), demonstrated biosynthesis of hydrocarbons in mammalian nerve tissue (2), and decreased hydrocarbon synthesis associated with neurological disorders (5,6) suggest important biological functions for this class of simple compounds.…”
mentioning
confidence: 99%