Biosynthesis of ZnO nanoparticles using Melia azedarach seed extract: Evaluation of the cytotoxic and antimicrobial potency

Dinga, Enathi; Mthiyane, Doctor Mziwenkosi Nhlanhla; Marume, Upenyu; Botha, Tarryn-L.; Horn, Suranie; Pieters, Rialet; Wepener, Victor; Ekennia, Anthony; Onwudiwe, Damian-C.

doi:10.1016/j.onano.2022.100068

Cited by 18 publications

(3 citation statements)

References 59 publications

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“…Comparable elemental impurities of plant-derived carbon and oxygen were reported in other studies (26,27). XRD data (Figure 5 no.36-1451).…”

Section: Antioxidant Activity Of Zinc Oxide Nanoparticlessupporting

confidence: 80%

Biosynthesis and In Vitro Antioxidant Activities of Zinc Oxide Nanoparticles with Turkish oregano (Origanum onites L.) Extract

YEŞİLOT,

AYDIN ACAR

2023

Turkish Journal of Health Science and Life

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Plant-mediated biosynthesis of metallic nanoparticles (NPs) occurs via biomolecules containing organic functional groups found in the plant. The aim of the study was to characterize and evaluate the antioxidant properties of zinc oxide nanoparticles (ZnO NPs) synthesized from Turkish oregano (Origanum onites L.), a traditional endemic plant. Some characteristic properties of ZnO NPs were determined by using the methods that ultraviolet visible spectroscopy (UV–Vis), scanning electron microscopy (SEM), Energy Dispersive X-ray analysis (EDX) and X-ray diffraction (XRD). UV–vis absorption peak of ZnO NPs observed at about 356 nm. Spherical shaped and nano-sized Zn ONPs has been detected by SEM. EDX analysis revealed that zinc is the primary constituent (50.69 %) with strong peaks at 1 keV. The average crystallite size of ZnO NPs has been showed at 30 nm by x-ray diffractometer. Antioxidant activity was investigated using a DPPH free radical quenching assay ZnO NPs demonstrated moderate antioxidant activity by scavenging 42.07%. Ultimately, the study shows that phyto-fabricated ZnO NPs were successfully synthesized and have a reasonable antioxidant effect.

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“…Comparable elemental impurities of plant-derived carbon and oxygen were reported in other studies (26,27). XRD data (Figure 5 no.36-1451).…”

Section: Antioxidant Activity Of Zinc Oxide Nanoparticlessupporting

confidence: 80%

Biosynthesis and In Vitro Antioxidant Activities of Zinc Oxide Nanoparticles with Turkish oregano (Origanum onites L.) Extract

YEŞİLOT,

AYDIN ACAR

2023

Turkish Journal of Health Science and Life

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“…It has also demonstrated antibacterial effectiveness against Gram-positive and Gram-negative bacteria with higher antagonistic activity, generating bacterial growth and inhibition [ 24 ]. Likewise, there are methods where this type of nanoparticle has been synthesized by the green route, and where excellent antibacterial activity has also been exhibited [ 25 ], besides applying it in food for similar purposes, too [ 26 ], and in animal nutrition, because good antimicrobial potency against E. coli and S. aureus has been reported [ 27 ]. In general, a positive response to a broad spectrum of pathogenic microorganisms has been obtained [ [28] , [29] , [30] , [31] ].…”

Section: Introductionmentioning

confidence: 99%

Enhanced antimicrobial efficacy of biogenic ZnO nanoparticles through UV-B activation: A novel approach for textile garment

Asmat-Campos,

Rojas-Jaimes,

Simbrón de la Cruz

et al. 2024

Heliyon

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“…Green synthesis route involves the use of diferent parts of plants, bacteria, fungi, and algae. Te biomolecules present in these sources are used to reduce and stabilize the NPs by preventing the agglomeration of grains during the preparation of NPs [48][49][50]. In this work, the green synthesis method which is an environmentally friendly, costefective, and nontoxic method in which Datura stramonium leaf extract has been applied for the synthesis of Co 3 O 4 @ZnO core-shell NPs as illustrated in Figure 1.…”

Section: Introductionmentioning

confidence: 99%

In Situ Green Synthesis of Co3O4@ZnO Core-Shell Nanoparticles Using Datura stramonium Leaf Extract: Antibacterial and Antioxidant Studies

Tadesse,

Ananda Murthy,

Ravikumar

et al. 2023

Bioinorganic Chemistry and Applications

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Investigating and synthesizing potent antibacterial NPs using biological methods is highly preferred, and it involves nontoxic, cost-effective, and environmentally friendly chemicals and methods. Antibiotic drug resistance and oxidative stress have become a serious public health issue worldwide. Hence, the key objective of this study was to biologically synthesize and characterize the potent antibacterial Co3O4@ZnO core-shell nanoparticles for the antibacterial application. The radical scavenging ability of green synthesized Co3O4@ZnO core-shell nanoparticles was also determined. In this study, Co3O4@ZnO core-shell nanoparticles (CZCS NPs) have been synthesized using three different core to shell materials ratios of Co3O4 to ZnO (0.5 : 0.25 CZCS (1), 0.5 : 0.5 CZCS (2), and 0.5 : 0.75 M CZCS (3)) by employing Datura stramonium leaf extract. The polycrystalline nature of Co3O4@ZnO core-shell nanoparticles was investigated using the XRD and SAED characterization techniques. The investigated nanostructure of Co3O4@ZnO core-shell nanoparticles appeared with Co3O4 as the core and ZnO as an outer shell. Additionally, a variety of physicochemical properties of the nanoparticles were determined using various characterization techniques. The average crystallite sizes of CZCS (1), CZCS (2), and CZCS (3) were found to be 24 ± 1.4 , 22 ± 1.5 , and 25 ± 1.5 nm, respectively. The band gap energy values for CZCS (1), CZCS (2), and CZCS (3) determined from the UV-DRS data were found to be 2.75, 2.76, and 2.73 eV, respectively. The high inhibition activities against S. aureus, S. pyogenes, E. coli, and P. aeruginosa bacterial strains were obtained for the small size CZCS (2) nanoparticles at the concentration of 100 mg/mL with 22 ± 0.34, 19 ± 0 . 32 , 18 ± 0.45 , and 17 ± 0 .32 mm values, respectively. The high inhibition performance of CZCS (2) nanoparticles against Gram-positive and Gram-negative bacteria which is even above the control drug ampicillin is because of its small size and synergistic effect. The percentage scavenging activity of Co3O4@ZnO core-shell nanoparticles was also studied and CZCS (2) nanoparticles showed a good scavenging capacity (86.87%) at 500 μg/mL with IC50 of 209.26 μg/mL.

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Biosynthesis of ZnO nanoparticles using Melia azedarach seed extract: Evaluation of the cytotoxic and antimicrobial potency

Cited by 18 publications

References 59 publications

Biosynthesis and In Vitro Antioxidant Activities of Zinc Oxide Nanoparticles with Turkish oregano (Origanum onites L.) Extract

Biosynthesis and In Vitro Antioxidant Activities of Zinc Oxide Nanoparticles with Turkish oregano (Origanum onites L.) Extract

Enhanced antimicrobial efficacy of biogenic ZnO nanoparticles through UV-B activation: A novel approach for textile garment

In Situ Green Synthesis of Co3O4@ZnO Core-Shell Nanoparticles Using Datura stramonium Leaf Extract: Antibacterial and Antioxidant Studies

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