Biotechnological Advancement in an Important Medicinal Plant, Withania coagulans: An Overview and Recent Updates

Rathore, Mangal S.; Khatri, Kapil; Kheni, Jasminkumar; Shekhawat, N. S.

doi:10.1007/978-981-13-0535-1_20

Cited by 4 publications

(4 citation statements)

References 51 publications

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“…The roots of ashwagandha are fleshy when dry, they're straight, spherical, tapering down, gradationally Unbranched Of ( 24 -26). Ten new phytoconstituents were linked from air-driedWithania coagulans fruit uprooted with methanol and their structures were grounded on their chemical and spectral data ( 27). colorful ingredients of Withania coagulans were estimated in three different excerpts videlicet, methanolic, hydroalcoholic, and chloroform.…”

Section: Rootsmentioning

confidence: 99%

The Phytochemical and Pharmacological Screening of Withania Coagulans

Sanskruti Pawar,

Shubhangi Manikpuriya,

Gajanan Sanap

2023

World J. Bio. Pharm. Health Sci.

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In ancient system of the drug, colorful shops shows to cure colorful health disordes and conditions. Withania coagulans Dunal, Is generally known as ‘ Indian bubbish maker ’ Or ‘ Vegetable Rennet ’ because The part of withaniai.E fruits and Leaves are used as a coagulant. Withania coagulans(Withania coagulans) dunal belongs To Family solanaceae.Withania coagulans dunal Is a argentine- whitish In colour, It's small under shrub It Is distributed In east of The mediterranean region. It Isone Of The most important medicinal factory and It's veritably useful In ayurveda. In ayurvedic system Of drug,Withania coagulans Is fxtensively Used In diabetic Cases, antimicrobial, antitumour and also shows other colorful exertion. Coagulin H Insulated FromWithania coagulans displayed effect On The vulnerable response. The Dried Flowers were uprooted consecutively by methanol and water. Withania coagulans Show remedial effect Of The Part of whole factory Withania coagulans dunal Is A Rigid, argentine- whitish Small Shrub, about 30- 150 Cm Altitudinous. The leaves are about2.5-7.5 Cm long and1.5 Cm broad. The Seeds Are Dark Brown, Observance Shaped, rough with sharp Fruity smell. dunal Flower may contain nioactive element to Treat colorful conditions. Withania coagulans is pharmacological Important remedial Factory, generally Known As Rishyagandha. It's used In treatment of colorful conditions like Indigestion, diabetes mellitus, liver diseases, sanctification Of blood and controls blood Pressure. In addition, It's reported To control tube glucose situations and precluding renal complications. A standard protocol was Followed For The birth Of Withania coagulans. The fruits of Withania coagulans 0.28 G/ 100 Ml) Were Soaked In distilled water overnight followed by a mechanical dissipation using A sterile cotton wood and filtration through rubbish cloth.

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Section: Rootsmentioning

confidence: 99%

The Phytochemical and Pharmacological Screening of Withania Coagulans

Sanskruti Pawar,

Shubhangi Manikpuriya,

Gajanan Sanap

2023

World J. Bio. Pharm. Health Sci.

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“…It occurs in Nepal and the northwest of India in the Indian subcontinent [2]. The National Medical Plant Board (NMBP) recognizes 24 species of Withania, but two of them stand out for their valuable medical properties [3]. These two species are known as Withania coagulans and W. somnifera, also known as ashwagandha.…”

Section: Introductionmentioning

confidence: 99%

“…These two species are known as Withania coagulans and W. somnifera, also known as ashwagandha. Both species contain valuable metabolites known as withanolides (WTDs), whose therapeutic potential has been extensively researched [1][2][3][4][5][6][7]. W. coagulans is used for a variety of medicinal purposes, so permanent stocks have been overexploited, known as withanolides (WTDs), whose therapeutic potential has been extensively researched [1][2][3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…Both species contain valuable metabolites known as withanolides (WTDs), whose therapeutic potential has been extensively researched [1][2][3][4][5][6][7]. W. coagulans is used for a variety of medicinal purposes, so permanent stocks have been overexploited, known as withanolides (WTDs), whose therapeutic potential has been extensively researched [1][2][3][4][5][6][7]. W. coagulans is used for a variety of medicinal purposes, so permanent stocks have been overexploited, and the species is endangered.…”

Section: Introductionmentioning

confidence: 99%

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Biotechnological Intervention and Withanolide Production in Withania coagulans

et al. 2023

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Withania coagulans (Stocks) Dunal is used in traditional medicine to treat diseases and has numerous pharmacological properties due to its biological compounds. The plant is a subshrub native to Asia, especially the tropical and temperate regions of western Asia. Its medicinal effects derive from its biological components, which are linked to human health. Conventional medicine uses these compounds to treat a variety of diseases, such as neurological issues, diabetes, and asthma. The long-term benefits of W. coagulans necessitate conservation strategies and plant biotechnological techniques such as micropropagation, synthetic seed, cell suspension, and hairy root elicitation technology, and genetic transformation can all play significant roles in conservation and sustainable utilization of the biological compounds for clinical uses. The objective of this review is to provide a comprehensive overview of the W. cogaulans medicinal properties, potential applications, and innovative approaches for sustainable utilization, making it a unique contribution to the existing body of knowledge. Multi-omics methods for the production of withanolides were also examined in order to gain a better understanding of the genome structure, prospective genes, and candidate proteins involved in the production.

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