Biotechnological production of l(+)-lactic acid from wood hydrolyzate by batch fermentation of Enterococcus faecalis

Wee, Young‐Jung; Yun, Jong-Sun; Park, Don-Hee; Ryu, Hwa-Won

doi:10.1023/b:bile.0000009464.23026.e0

Cited by 82 publications

(66 citation statements)

References 9 publications

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“…Lactic acid has many applications as a food additive, acidulant, as well in the production of biodegradable polylactic acid [81,82]. Food-grade lactic acid has a price ranging between $1.38 per kilogram (50% purity) and $1.88 per kilogram (88% purity) [83,84]. Compared to traditional chemical synthesis methods, microbial conversion of lactic acid favors the formation of one specific configuration, either D-or L-, due to the high specificity of lactate dehydrogenase (LDH) [28,29], a property that can simplify downstream processes such as separation and purification.…”

Section: Escherichia Speciesmentioning

confidence: 99%

“…The yield of hydrogen and ethanol were 0.74 and 0.92 mol/mol glycerol respectively. The consumption of glycerol can be increased from 45.7% to 84.5% through the application of a potential of 0.2 V. Mixed culture MECs with a single chamber design can produce hydrogen yields of 3.9 mol/mol and 5.4 mol/mol glycerol, higher than pure culture MECs, with applied voltages of 0.9 and 1.0 V [79,80]. The application of pretreatments like heat shock should be considered to before inoculation as a method to prevent growth of methanogens.…”

Section: Microbial Electrochemical Conversionmentioning

confidence: 99%

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Microbial Conversion of Waste Glycerol from Biodiesel Production into Value-Added Products

Lesnik

Liang

2013

Energies

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Biodiesel has gained a significant amount of attention over the past decade as an environmentally friendly fuel that is capable of being utilized by a conventional diesel engine. However, the biodiesel production process generates glycerol-containing waste streams which have become a disposal issue for biodiesel plants and generated a surplus of glycerol. A value-added opportunity is needed in order to compensate for disposal-associated costs. Microbial conversions from glycerol to valuable chemicals performed by various bacteria, yeast, fungi, and microalgae are discussed in this review paper, as well as the possibility of extending these conversions to microbial electrochemical technologies.

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Section: Escherichia Speciesmentioning

confidence: 99%

Section: Microbial Electrochemical Conversionmentioning

confidence: 99%

Microbial Conversion of Waste Glycerol from Biodiesel Production into Value-Added Products

Lesnik

Liang

2013

Energies

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“…Wood is currently considered as a fairly attractive raw material for use in its production [10][11][12]. However, it has become necessary, in recent years, to develop an alternative nitrogen source which is cheaper than the yeast extract traditionally employed in the cultivation of lactic acid bacteria, because production costs are highly dependent on the nitrogen source cost, as well as the carbon source cost [13].…”

Section: Introductionmentioning

confidence: 99%

Batch and repeated batch production of l(+)-lactic acid by Enterococcus faecalis RKY1 using wood hydrolyzate and corn steep liquor

Wee

Yun

Kim

et al. 2006

J IND MICROBIOL BIOTECHNOL

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Lactic acid production was investigated for batch and repeated batch cultures of Enterococcus faecalis RKY1, using wood hydrolyzate and corn steep liquor. When wood hydrolyzate (equivalent to 50 g l À1 glucose) supplemented with 15-60 g l À1 corn steep liquor was used as a raw material for fermentation, up to 48.6 g l À1 of lactic acid was produced with, volumetric productivities ranging between 0.8 and 1.4 g l À1 h À1 . When a medium containing wood hydrolyzate and 15 g l À1 corn steep liquor was supplemented with 1.5 g l À1 yeast extract, we observed 1.9-fold and 1.6-fold increases in lactic acid productivity and cell growth, respectively. In this case, the nitrogen source cost for producing 1 kg lactic acid can be reduced to 23% of that for fermentation from wood hydrolyzate using 15 g l À1 yeast extract as a single nitrogen source. In addition, lactic acid productivity could be maximized by conducting a cell-recycle repeated batch culture of E. faecalis RKY1. The maximum productivity for this process was determined to be 4.0 g l À1 h À1 .

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“…26 Few studies have reported the dilute-acid hydrolysis of lignocellulosic biomass from wood and the use of microorganism with ability to produce lactic acid in these hydrolysates. 18,[27][28][29] Optimization of hydrolysis conditions is necessary for improving the efficiency of biomass conversion processes. Rafiqul et al 30 pointed out that xylose release via acid bioconversion of Meranti wood sawdust depended on a number of process factors like temperature, H 2 SO 4 concentration, and residence time.…”

Section: Introductionmentioning

confidence: 99%

Statistical Optimization of Dilute Acid Hydrolysis of Wood Sawdust for Lactic Acid Production

Nancib¹

2017

JABB

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Abbreviations: SW, sawdust wood; CCD, central composite design; LAB, lactic acid bacteria; L-LDH, L-lactate dehydrogenase; RSM, response surface methodology; 3D, 3-dimensional; MSW, meranti wood sawdust; OFI, Opuntia ficus indica IntroductionLactic acid has a wide application in food, pharmaceutical, leather, cosmetic applications, textile, and polylactic acid industries.1-3 Lactic acid can be produced either by fermentation or by chemical synthesis. But the biotechnological fermentation process has received significant importance due to environmental concerns, use of renewable resources instead of petrochemicals, low production temperature, low energy requirements, and high purity. Mammalian cells only contain L-lactate dehydrogenase (L-LDH), so L(+) form of lactic acid is used for food and drug industry, because the human body is only adapted to assimilate this form by the action of the enzyme L-LDH whereas D-lactic acid is often harmful to human metabolism, his accumulation in the blood can cause acidosis. 4,5 Lactic acid can be synthesized by microbial fermentation of the various raw materials such as molasses, 6 whey, 7 and date juice. 8 As in any industrial organic acid or solvent fermentation, the main economic factors are the choice and cost of the substrate and the cost of recovery in downstream processing. Feedstock that would reduce the processing cost would greatly enhance the competitiveness of fermentative lactate production. Many efforts have been made to develop biotechnologies for lactate generation from such a cheap, abundant and renewable substrate. Recently, fermentation of non-food biomass has also gained considerable attention due to the forthcoming scarcity of fossil fuels and the increased lack of food and feed supplies over the world. Biomass of lignocelluloses is a low-cost and extensively available renewable carbon source as an alternative to the conventional feed stocks.9-11 Lignocellulosic biomass is primarily composed of cellulose, hemicellulose, and lignin. 12,13 A cellulosic feedstock (such as wood) has been widely used to replace refined sugar, and been utilized for the production of ethanol, 14,15 single cell protein, 16 xylitol 17 and organic acid such as lactic acid. 18The conversion of wood to lactic acid is more challenging due to the complex structure of the lingocellulose. The three polymers of Lignocellulosic biomass are arranged to form a highly recalcitrant structure, 19 hindering the availability of carbohydrates for fermentation processes, representing a high barrier for the bioconversion of lignocellulosic material. In fact it is necessary to pretreat the wood to alter its structural and chemical composition to facilitate hydrolysis of carbohydrates to fermentable sugars. 20,21 Pretreatment uses various techniques, including ammonia fiber explosion, chemical treatment, biological treatment, and steam explosion, to alter the structure of cellulosic biomass to make cellulose more accessible. Conversion of wood lignocellulosic biomass to glucose and other monomeric suga...

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Biotechnological production of l(+)-lactic acid from wood hydrolyzate by batch fermentation of Enterococcus faecalis

Cited by 82 publications

References 9 publications

Microbial Conversion of Waste Glycerol from Biodiesel Production into Value-Added Products

Microbial Conversion of Waste Glycerol from Biodiesel Production into Value-Added Products

Batch and repeated batch production of l(+)-lactic acid by Enterococcus faecalis RKY1 using wood hydrolyzate and corn steep liquor

Statistical Optimization of Dilute Acid Hydrolysis of Wood Sawdust for Lactic Acid Production

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