1990
DOI: 10.1016/0753-3322(90)90171-5
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Biotin for diabetic peripheral neuropathy

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Cited by 44 publications
(23 citation statements)
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“…Although not a widely used regimen, high doses of biotin (10 mg/day) have been reported to improve symptoms of encephalopathy and peripheral neuropathy in patients with renal failure and undergoing chronic hemodialysis (6 ). In addition, it has been used for patients with diabetic peripheral neuropathy (7,8 ).…”
Section: Discussionmentioning
confidence: 99%
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“…Although not a widely used regimen, high doses of biotin (10 mg/day) have been reported to improve symptoms of encephalopathy and peripheral neuropathy in patients with renal failure and undergoing chronic hemodialysis (6 ). In addition, it has been used for patients with diabetic peripheral neuropathy (7,8 ).…”
Section: Discussionmentioning
confidence: 99%
“…Although not a widely used regimen, high doses of biotin (10 mg/day) have been reported to improve symptoms of encephalopathy and peripheral neuropathy in patients with renal failure and undergoing chronic hemodialysis (6 ). In addition, it has been used for patients with diabetic peripheral neuropathy (7,8 ).Biotin is recognized as a potential interferent in PTH and other assays on the Elecsys platform, and it is recommended in the product insert that samples from patients receiving high biotin doses of Ͼ5 mg/day be collected at least 8 h after biotin administration (9 ). In the Elecsys intact PTH assay, a biotinylated anti-PTH monoclonal antibody and a ruthenium-labeled anti-PTH monoclonal antibody form a sandwich complex with PTH, after which streptavidin-coated microparticles are added to magnetically separate out the sandwich complex via biotin and streptavidin interaction.…”
mentioning
confidence: 99%
“…Biotin seems to regulate and ameliorate glucose homeostasis, because it favors an anti-hyperglycemic effect (with the above said enzymes) and hyperglycemic effect (with the regulation of the hepatic phosphoenolpyruvate carboxykinase, a gluconeogenic enzyme) [3].…”
mentioning
confidence: 99%
“…This was followed up by injections three times a week for another six weeks and oral administration of 5 mg daily. All three patients noted improvements with 4-8 weeks although nerve conduction studies found that it had only slightly improved or not at all [186].…”
Section: Role Of Biotin In the Peripheral Nervous Systemmentioning
confidence: 99%
“…Currently, no research has been conducted on biotin and CIPN, but there has been studies conducted for uremic [184,185] and diabetic neuropathy [186]. For uremic neuropathy, a small study conducted on nine patients undergoing dialysis that were suffering from PN were supplemented 10 mg of biotin in three divided doses for 1-4 years [184].…”
Section: Role Of Biotin In the Peripheral Nervous Systemmentioning
confidence: 99%