Biotransformation of 20(S)-protopanaxatriol by Mucor racemosus and the anti-cancer activities of some products

Abstract

Biotransformation by M. racemosus AS 3.205 was an effective approach to produce new derivatives of 20(S)-protopanaxatriol.

Production of biotechnological useful metabolites by Mucor racemosus in Czapek-Dox liquid media supplemented with synthetic detergent

“…Recent studies have shown that M. racemosus may be employed to biotransform some steroid compounds, such as progesterone [15], methyltestosterone [16] and 20(s)-protopanaxatriol [17] to intermediates with anti-cancer activities. Likewise, the fungus grown on synthetic and organic substrates may be used for the production of various enzymes such as invertase, alkaline phosphatase, protease and lipase, which are of biotechnological and bioremediation interest [18].…”