2021
DOI: 10.1039/d1en00594d
|View full text |Cite
|
Sign up to set email alerts
|

Biotransformations and cytotoxicity of graphene and inorganic two-dimensional nanomaterials using simulated digestions coupled with a triculture in vitro model of the human gastrointestinal epithelium

Abstract: Background: Engineered nanomaterials (ENMs) have already made their way into myriad applications and products across multiple industries. However, the potential health risks of exposure to ENMs remain poorly understood. This...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
19
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 15 publications
(20 citation statements)
references
References 78 publications
1
19
0
Order By: Relevance
“…The TEM images depict the sheet-like structure of the WS 2 nanosheets with an average lateral size of 200 ± 37 nm (Figure A,C), agreeing well with the average lateral dimensions found by NTA and DLS (Supporting Information Figures S1 and S2). The thickness of the nanosheets measured by AFM was 5.1 ± 1.4 nm (Figure B,D), consistent with previous findings . These measurements suggested that there was no aggregation of the nanosheets upon material transportation and storage.…”
Section: Resultssupporting
confidence: 91%
See 3 more Smart Citations
“…The TEM images depict the sheet-like structure of the WS 2 nanosheets with an average lateral size of 200 ± 37 nm (Figure A,C), agreeing well with the average lateral dimensions found by NTA and DLS (Supporting Information Figures S1 and S2). The thickness of the nanosheets measured by AFM was 5.1 ± 1.4 nm (Figure B,D), consistent with previous findings . These measurements suggested that there was no aggregation of the nanosheets upon material transportation and storage.…”
Section: Resultssupporting
confidence: 91%
“…The thickness of the nanosheets measured by AFM was 5.1 ± 1.4 nm (Figure 1B,D), consistent with previous findings. 19 These measurements suggested that there was no aggregation of the nanosheets upon material transportation and storage.…”
Section: ■ Materials and Methodsmentioning
confidence: 99%
See 2 more Smart Citations
“…However, toxicological assessment of the GO small intestinal digesta over 24 h did not show any acute cytotoxicity. In the subsequent study by the same authors, a panel of 11 industrially relevant 2D materials, including graphene, GO, partially reduced GO (prGO), rGO, hBN, MoS 2 , and WS 2 , were evaluated by using simulated GI digestions and a triculture model of the human small intestinal epithelium . The 2D materials were dispersed in a fasting food model and subjected to 3-phase simulated digestion (representative of the oral cavity, gastric tract, and small intestine).…”
Section: Impact On the Gastrointestinal Systemmentioning
confidence: 99%