Biparietal/transverse abdominal diameter ratio ≤ 1: potential marker for open spina bifida at 11–13‐week scan

Simon, Emmanuel; Arthuis, Chloé; Haddad, Georges; Bertrand, P.; Perrotin, Franck

doi:10.1002/uog.13406

Cited by 36 publications

(40 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several new markers for OSB were added in the last years to the multitude of early features of this pathology. It seems that the BPD/transverse abdominal diameter ratio improves considerably the diagnostic performance of using BPD measurement alone, to 76.9% [29,35]. Also, combining alpha fetoprotein and BPD with free β-hCG as part of first trimester aneuploidy screening, would allow early detection of about two-thirds of cases [36].…”

Section: Limitations Of the First Trimester Scanmentioning

confidence: 99%

CNS Abnormalities at 11-14 Weeks

Iliescu¹,

Comanescu²

2017

Neonat Pediatr Med

View full text Add to dashboard Cite

Section: Limitations Of the First Trimester Scanmentioning

confidence: 99%

CNS Abnormalities at 11-14 Weeks

Iliescu¹,

Comanescu²

2017

Neonat Pediatr Med

View full text Add to dashboard Cite

“…A ratio between the BPD and the transverse abdominal diameter lower than 1 is more practical to use in clinical practice as it obliviates the need for nomograms and will detect 69% of OSB cases for a similar 5% false‐positive rate. The use of the BPD/abdominal diameter ratio in combination with a BPD less than the fifth percentile has the advantage of increasing the specificity (false positive 0.6%) but results in a lower detection rate (39%) . Combining BPD measurements with first‐trimester maternal serum alpha‐fetoprotein and free beta‐hCG improves detection rates only marginally and has not gained widespread acceptance (70% sensitivity for 10% false positives) …”

Section: Anomalies Of the Fetal Central Nervous Systemmentioning

confidence: 99%

Sonographic detection of central nervous system defects in the first trimester of pregnancy

et al. 2016

View full text Add to dashboard Cite

The fetal central nervous system can already be examined in the first trimester of pregnancy. Acrania, alobar holoprosencephaly, cephaloceles, and spina bifida can confidently be diagnosed at that stage and should actively be looked for in every fetus undergoing first-trimester ultrasound. For some other conditions, such as vermian anomalies and agenesis of the corpus callosum, markers have been identified, but the diagnosis can only be confirmed in the second trimester of gestation. For these conditions, data on sensitivity and more importantly specificity and false positives are lacking, and one should therefore be aware not to falsely reassure or scare expecting parents based on first-trimester findings. This review summarizes the current knowledge of first-trimester neurosonography in the normal and abnormal fetus and gives an overview of which diseases can be diagnosed.

show abstract

“…Spina bifida is a condition characterised by a cleft, defect or failure of closure to the neural tube . This incomplete development of the spinal cord can cause spinal cord, nerves roots and meninges to be exposed at a particular defect level . Within the early embryological stages, the neural tube originates as a thickened ectoderm .…”

Section: Introductionmentioning

confidence: 99%

“…Spina bifida can be characterised into a few major types. Spina bifida ‘occulta’ or closed neural tube defect (NTD) is, as the name suggests, a spinal defect with no opening to the skin at this particular point . Symptoms can be quite mild, and this particular type can be quite difficult to detect on ultrasound .…”

Section: Introductionmentioning

confidence: 99%

The detection of spina bifida at 11–13+6 weeks' gestation

Borg

2016

Sonography

View full text Add to dashboard Cite

Prenatal detection of spina bifida during a 12‐week ultrasound can be a complex diagnosis. Spina bifida is a condition characterised by failure of the neural tube to form during embryological development, and the early manifestations in the head and spine may be detected on ultrasound. A good understanding of the characteristic intracranial ultrasound signs within the first trimester, such as the intracranial translucency, cisterna magna and aqueduct of Sylvius will allow for greater awareness and detection of spina bifida at this gestation. Other markers such as biparietal diameter, transverse abdominal diameter, brain stem to occiput bone and frontomaxillary facial angle have been shown to greatly increase the detection of such a condition. Recent advances in technology such as 3D sonography and transvaginal scanning have greatly increased visualisation and provided greater confidence in detection. At present, there is no formal direction put forward from major ultrasound bodies for the detection, at this gestation; however, bodies such as ISUOG have created awareness. Future developments suggest that the visualisation of the intracranial translucency and aqueduct of Sylvius will become a standard practice while scanning at this gestation.

show abstract

Biparietal/transverse abdominal diameter ratio ≤ 1: potential marker for open spina bifida at 11–13‐week scan

Abstract: ABSTRACT

Cited by 36 publications

References 34 publications

CNS Abnormalities at 11-14 Weeks

CNS Abnormalities at 11-14 Weeks

Sonographic detection of central nervous system defects in the first trimester of pregnancy

The detection of spina bifida at 11–13+6 weeks' gestation

Contact Info

Product

Resources

About