Biperiden for treatment of somnambulism in adolescents and adults with or without epilepsy: Clinical observations

Hodoba, Danilo; Schmidt, Dieter

doi:10.1016/j.yebeh.2012.09.009

Cited by 6 publications

(4 citation statements)

References 26 publications

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“…Dessa forma, não é possível afirmar que todos os antiparkinsonianos foram adquiridos para o tratamento da DP. O fármaco biperideno, por exemplo, um dos que apresentou o maior volume de aquisição, é bastante utilizado paraoutras condições, como no tratamento de efeitos colaterais em pacientes que utilizam antipsicóticos 58 , em casos refratários de sonambulismo 59 e no tratamento da dependência de cocaína/crack 60 . Outro aspecto importante é que os registros de compras de medicamentos no SIAD não permitem identificar, sistematicamente, quais são as compras efetuadas em decorrência de mandados judiciais, os quais podem ter interferido na execução da política de aquisição de medicamentos pelo estado de Minas Gerais.…”

Section: Discussionunclassified

Tendência nos gastos com medicamentos neuropsiquiátricos em Minas Gerais, Brasil: há aumento da oferta de antiparkinsonianos?

Carvalho

Alves

Luz

2021

Ciênc. saúde coletiva

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Resumo Medicamentos neuropsiquiátricos são utilizados para variadas condições neurológicas e psiquiátricas. O objetivo deste artigo é analisar evolução e determinantes dos gastos públicos com esses medicamentos em Minas Gerais de 2010 a 2017. Dados do Sistema Integrado de Administração de Materiais e Serviços (SIAD) foram usados para estimar volumes de aquisição e gastos. Realizou-se análise de decomposição e, para os medicamentos antiparkinsonianos foi avaliado o elenco adquirido, aplicando-se, ainda, a técnica de Drug Utilization (DU90%). O gasto anual diminuiu 36%, passando de R$ 111,7 milhões em 2010 para R$ 40,9 milhões em 2017, tendo como fatores determinantes a queda de preços e de volume, associada às mudanças do drugmix, optando-se pela aquisição de produtos, em média, mais caros. Destaca-se o aumento dos gastos para a classe dos antiparkinsonianos, porém, com significativa mudança no elenco adquirido. Esse estudo contribuiu para um melhor entendimento dos gastos públicos com medicamentos neuropsiquiátricos. A redução do volume pode elevar o risco de desabastecimento. Com relação aos antiparkinsonianos, não há evidências que sugiram aumento da oferta para a população.

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Section: Discussionunclassified

Tendência nos gastos com medicamentos neuropsiquiátricos em Minas Gerais, Brasil: há aumento da oferta de antiparkinsonianos?

Carvalho

Alves

Luz

2021

Ciênc. saúde coletiva

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“…Anticholinergic medication is used to address a proposed cholinergic mechanism in sleepwalking (e.g. Hodoba & Schmidt, 2012). Atypical antipsychotics are thought to decrease slow-wave sleep (Gill, Pillai, Koh, & Jambunathan, 2011).…”

Section: Interventions For Sleepwalkingmentioning

confidence: 99%

A systematic review of treatments for sleepwalking: 100 years of case studies

Stallman¹,

Kohler²

2016

Sleep Hypn

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While generally harmless, sleepwalking can result in injury to the sleepwalker and/or others, prompting help-seeking. This is the first study to systematically review the scientific evidence underpinning treatments for sleepwalking. A literature search of CINAHL, EMBASE, PsycINFO, PubMed, and ScienceDirect was conducted with the keywords 'sleepwalking' OR 'somnambulism', current to 29 February 2016. Studies were included if they reported on any intervention for sleepwalking.Of the original 53 sourced papers, 44 met the inclusion criteria and were subsequently included for review. None had a methodology that could demonstrate efficacy or effectiveness. Case and case series reports dominate the literature with patients treated with a range of psychological, pharmacological and other interventions. While the results of this review highlight potential treatments, well-designed randomized control trials of theoretically supported interventions that include assessment of adverse effects are urgently needed. Psychological interventions-scheduled waking and hypnosis-are potential first line interventions for evaluation, especially with children, as they are theoretically grounded, case studies suggest they may be effective, and they do not have the side-effects of pharmacological interventions.

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“…In a study by Guilleminault et al, four out of five subjects placed on clonazepam had limited results at 3 months follow-up, reporting only a decrease in the frequency of sleepwalking events under particularly high daytime stress [63]. Cases of remission after treatment with olanzapine [64] and biperiden [65] have been reported. With no high-quality evidence to support recommendations for treatments of somnambulism, a patienttailored approach is recommended.…”

Section: Sleepwalkingmentioning

confidence: 99%

“…As with the other disorders of arousals, patients should antidepressants, SSRIs such as paroxetine [58], imipramine [59], clomipramine, sertraline [61]) • Antipsychotics (e. g., quetiapine [60], temazepam [61], olanzapine [64], and biperiden [65] be taught to avoid sleep deprivation and other trigger factors such as alcohol, stress, and drugs. Behavioral methods such as psychotherapy, relaxation therapy, autogenic training, and hypnosis can be used to prevent ST [52].…”

Section: Sleep Terrorsmentioning

confidence: 99%

Disorders of Arousal

Galbiati

Manni

Terzaghi

et al. 2016

Curr Sleep Medicine Rep

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Sleepwalking, sleep terrors, and confusional arousals are non-REM sleep parasomnias grouped under the specific category of disorders of arousal (DOA). These conditions are characterized by incomplete arousals from deep sleep that lead to a broad variety of emotional and motor behaviors. The advent of electroencephalography (EEG) and the discovery of rapid eye movement (REM) sleep as opposed to non-REM sleep allowed researchers to consider these phenomena from a neurophysiological rather than a purely psychopathological perspective. The utilization of new neurophysiologic techniques such as high-density scalp EEG, stereo-EEG, and advanced signal analysis methods shed further light on the mechanisms underpinning DOA and supported the notion that they should be viewed within the frame of the so-called dissociate state of being as intermediate state between wake and NREM sleep. Furthermore, other important issues like the boundaries between motor-behavioral manifestations in DOA and NFLE, neurocognitive functions, the occurrence of mentation/dream imagery during episodes in DOA and DOA daytime consequences, and treatment are still matters of debate.

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Biperiden for treatment of somnambulism in adolescents and adults with or without epilepsy: Clinical observations

Cited by 6 publications

References 26 publications

Tendência nos gastos com medicamentos neuropsiquiátricos em Minas Gerais, Brasil: há aumento da oferta de antiparkinsonianos?

Tendência nos gastos com medicamentos neuropsiquiátricos em Minas Gerais, Brasil: há aumento da oferta de antiparkinsonianos?

A systematic review of treatments for sleepwalking: 100 years of case studies

Disorders of Arousal

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