Bipolar Disorder in Late Life: A Review

Chen, Stephen T.; Altshuler, Lori L.; Spar, James E.

doi:10.1177/089198879801100107

Cited by 19 publications

(9 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This percentage largely reflects literature findings on the "treated prevalence" rates of elderly mania [8,9]. The reported decrease of the prevalence of manic episodes in late life could be attributed to disorder-related factors (e.g.…”

Section: Discussionsupporting

confidence: 81%

Bipolar disorder in late life: clinical characteristics in a sample of older adults admitted for manic episode

Benedetti

Scarpellini

Casamassima

et al. 2008

Clinical Practice and Epidemiology in Mental Health

View full text Add to dashboard Cite

BackgroundAlthough manic episodes in older adults are not rare, little published data exist on late-life manic episodes. Resistance to treatment and concomitant neurological lesions are frequent correlates of elderly mania. The aim of this study was to investigate the prevalence of hospitalizations due to mania in patients older than 64 years through a period of 5 years in an Italian public psychiatric ward. Moreover, we aimed at describing clinical presentation of elderly manic episodes.MethodsA retrospective chart review was conducted in order to describe clinical presentation of 20 elderly patients hospitalized for manic episode; moreover, we compared age at onset, the presence of family history for mood disorders, psychosis and irritability between the elderly group and a matched group of 20 younger manic inpatients.ResultsSeven percent of the whole inpatient elderly people suffered from mania. Half of those patients had a mood disorder age at onset after 50 years and 5 patients were at their first manic episode. Geriatric- and adulthood mania showed similar clinical presentation but younger people had more frequently a mood disorders family history.ConclusionHalf of our older manic inpatients consisted of "classic" bipolar patients with an extension of clinical manifestations into later life; the other half of our sample was heterogeneous, even though it was not possible to identify clearly which patients may have had vascular lesions related to the onset of mania.

show abstract

Section: Discussionsupporting

confidence: 81%

Bipolar disorder in late life: clinical characteristics in a sample of older adults admitted for manic episode

Benedetti

Scarpellini

Casamassima

et al. 2008

Clinical Practice and Epidemiology in Mental Health

View full text Add to dashboard Cite

show abstract

“…Many of these reviews have been targeted toward the clinician, and they have relied heavily on extrapolating data from other psychiatric disorders in late life or from younger people with bipolar disorder. Reviews that have more systematically critiqued available data need to be updated (30–33).…”

mentioning

confidence: 99%

“…Patient selection criteria. As noted in other reviews of bipolar disorder in older people (30, 32, 33), the definition of age of onset varied widely across studies in several ways, which likely contributes to inconsistency across investigations. Studies varied in whether they reported onset of affective symptoms, full‐blown depression or mania, or psychiatric hospitalization.…”

mentioning

confidence: 99%

Bipolar disorder in older adults: a critical review

2004

View full text Add to dashboard Cite

show abstract

“…Menopause is one of the factors that may influence onset, presentation and course of mood disorders in women after 40 years. Family history of mood disorder is less common, and neurological and vascular disorders are commoner in late-onset depression than in early-onset depression [28, 29]. …”

Section: Discussionmentioning

confidence: 99%

Female Depression before and after Menopause

Benazzi¹

2000

Psychother Psychosom

View full text Add to dashboard Cite

Background: There is no clear association between menopause and depression. Aim of the study was to compare female depression with onset before menopause with female depression with onset after menopause, to find out if endocrinological changes had an impact on depression. Methods: Five hundred and twelve consecutive unipolar and bipolar I/II depressed outpatients were interviewed with the Structured Clinical Interview for DSM-IV, the Montgomery-Asberg Depression Rating Scale and the Global Assessment of Functioning scale. Patients were divided into patients with depression/mania onset before 40 and after 40. Results: Female depression with onset after 40 had a significantly shorter duration of illness, fewer recurrences, fewer patients with atypical features, fewer bipolar II patients and more unipolar patients than female depression with onset before 40. Male depression with onset after 40 had a significantly shorter duration of illness and fewer patients with atypical features than male depression with onset before 40. Conclusions: Some features were common to both female and male depression with onset after 40. Female depression with onset after 40 had significantly more unipolar and fewer bipolar II patients, than female depression with onset before 40. Different frequency of unipolar and bipolar II patients suggests that the biology of depression in menopause women may be different from that of women not in menopause, and from that of male depression with onset after 40. Differences may be related to menopause.

show abstract

Bipolar Disorder in Late Life: A Review

Cited by 19 publications

References 45 publications

Bipolar disorder in late life: clinical characteristics in a sample of older adults admitted for manic episode

Bipolar disorder in late life: clinical characteristics in a sample of older adults admitted for manic episode

Bipolar disorder in older adults: a critical review

Female Depression before and after Menopause

Contact Info

Product

Resources

About