Bipolar disorder in youth

Carlson, Gabrielle A.; Meyer, Stephanie

doi:10.1007/s11920-000-0051-1

Cited by 11 publications

(11 citation statements)

References 76 publications

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“…Although a DSM-III-R diagnosis of mania has been reported in about 16% of outpatient users 12 years of age or younger,12 these data suggest that manic symptoms (as opposed to a DSM-IV diagnosis of bipolar disorder) may be even more common in young outpatient utilizers. Participating children who scored positive for symptoms of mania display very different behavior than children who scored negative, as noted in a number of previous studies examining symptoms in bipolar youth compared to youth with other diagnoses 11, 33, 48…”

Section: Discussionmentioning

confidence: 68%

Longitudinal Assessment of Manic Symptoms (LAMS) Study

Horwitz¹,

Demeter²,

Pagano³

et al. 2010

J. Clin. Psychiatry

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Objective To describe the design of a longitudinal study of youth with elevated symptoms of mania (ESM) as well as the prevalence and correlates of manic symptoms. Bipolar disorder in youth is serious and is surrounded by controversy about its phenomenology, course and treatment. Yet, there are no longitudinal studies of youth selected only for ESM, the phenomenological hallmark. The study’s objective is to document the rate and sociodemographic correlates of ESM in children attending outpatient psychiatric clinics. Method Parents of 3329 6–12 year old children visiting 10 outpatient clinics were asked to complete the Parent General Behavior Inventory-10 Item Mania Scale (PGBI-10M). Children with PGBI-10M scores ≥ 12 (ESM+) and a matched sample of screen negatives (ESM−) were invited to enroll in the longitudinal study. Results Most (N=2622, 78.8%) participated. Nonparticipants were slightly younger (M=9.1 years, SD=2.0 versus 9.4 years, SD=2.0; t=4.42, df=3327, p<0.001). Nearly half (43%) were ESM+; these were more likely to be Latino (4.2% versus 2.5%, X2 =5.45, df=1, p=0.02), younger (M=9.3 years, SD=2.0 versus M=9.6 years, SD=1.9, t=3.8, df=2620, p<0.001) and insured by Medicaid (48.4% versus 35.4%, X2 =45.00, df=1, p<0.001). There were no sociodemographic differences between those who did versus did not agree to enroll in the longitudinal portion (ESM+ N=621, 55.2%; ESM− N=503, 44.8%). Four items best discriminated ESM+ from ESM−. These were not the most commonly endorsed but were indicative of behavioral extremes. Conclusions Data suggest ESM+ is not rare in 6 to 12 year olds. ESM+ children show behavioral extremes including rapid mood shifts compared to ESM− children.

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Section: Discussionmentioning

confidence: 68%

Longitudinal Assessment of Manic Symptoms (LAMS) Study

Horwitz¹,

Demeter²,

Pagano³

et al. 2010

J. Clin. Psychiatry

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“…For example, caregiver reports indicate there are executive functioning deficits in adolescents with bipolar disorder (DelBello et al, 2004) and a longitudinal study of young adults with bipolar disorder has reported attentional deficits throughout adolescence (Carlson and Meyer, 2000). A recent study by Goldstein et al (2006) reported deficits in social behavior and interpersonal functioning in adolescents with bipolar disorder, even when relatively well.…”

Section: Neuropsychological Profile Of Juvenile Bipolar Disorder Compmentioning

confidence: 99%

Do Cognitive Deficits in Juvenile Bipolar Disorder Persist Into Adulthood?

Cahill

Green²,

Jairam

et al. 2007

Journal of Nervous &Amp; Mental Disease

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This article reviews neuropsychological research in adults with bipolar disorder and compares the findings with emergent data on neuropsychological function in juvenile bipolar disorder. Despite a recent surge of interest in childhood onset bipolar disorder, there remains a scarcity of neuropsychological literature investigating this population. From the study of adult bipolar disorder a substantial body of literature points to the existence of trait deficits in verbal and executive function that are detectable even during euthymia. In the nascent literature on neuropsychology in early onset bipolar, there is growing evidence to suggest that some of the deficits apparent in adults are also discernible in adolescents. Precise knowledge about when, how, and why these deficits appear requires future research of prodromal changes in neurocognition in childhood and adolescent bipolar disorder.

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“…B ipolar disorder has been observed in adolescents (Carlson and Strober, 1978;Lewinsohn et al, 1995) and prepubertal school-age children (Carlson 1998;Carlson and Meyer 2000;Geller et al 1994Geller et al , 1998Weller et al 1986b;Wozniak et al 1995). It is of interest to determine if the illness occurs in preschool children.…”

Section: Introductionmentioning

confidence: 99%

Mania in Six Preschool Children

Tumuluru

Weller

Fristad

et al. 2003

Journal of Child and Adolescent Psychopharmacology

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At least nine cases of apparent preschool manic-depressive illness have been previously reported in the literature. In each of these children, a strong family history of affective illness was noted. In this report, the case histories of six preschool children ages 3 to 5 years with bipolar illness are summarized. These six were obtained from a sample of 36 consecutively hospitalized preschool children. Thus 17% of these hospitalized preschool children had bipolar illness. All had irritable mood, strong family history of affective illness, and previous presentation with symptoms of attention deficit hyperactivity disorder. They were diagnosed following a thorough clinical interview. Five children were treated with lithium; all five improved. Preschool mania exists as an identifiable entity and may respond to classic pharmacologic treatments.

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Bipolar disorder in youth

Cited by 11 publications

References 76 publications

Longitudinal Assessment of Manic Symptoms (LAMS) Study

Longitudinal Assessment of Manic Symptoms (LAMS) Study

Do Cognitive Deficits in Juvenile Bipolar Disorder Persist Into Adulthood?

Mania in Six Preschool Children

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