1993
DOI: 10.1016/s0095-5108(18)30396-8
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Birth Asphyxia and the Neonatal Brain: What Do We Know and When Do We Know It?

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Cited by 59 publications
(26 citation statements)
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“…There has been some debate about what proportion of neonatal injury is attributable to hypoxic-ischaemic injury, 32 and to what extent the signs of postaxphyxial encephalopathy reflect chronic brain lesions of antepartum onset 2324 32 But in the clinical context, MRI is a considerable improvement because it allows us to estimate how many complications really are preventable.…”
Section: Discussionmentioning
confidence: 99%
“…There has been some debate about what proportion of neonatal injury is attributable to hypoxic-ischaemic injury, 32 and to what extent the signs of postaxphyxial encephalopathy reflect chronic brain lesions of antepartum onset 2324 32 But in the clinical context, MRI is a considerable improvement because it allows us to estimate how many complications really are preventable.…”
Section: Discussionmentioning
confidence: 99%
“…It is clear that the diagnosis of birth asphyxia can only be made retrospectively [76]; it is the sequence of symptoms and signs and how the brain and other organs react over time that indicate the diagnosis. Therefore, neither the diagnosis nor the prognosis can be affirmed until some time after birth.…”
Section: Oxidative Stress and Perinatal Asphyxiamentioning
confidence: 99%
“…These variables are congenital malformations (21,(34)(35)(36), multiple pregnancy (37)(38)(39), unhealthy placenta and placenta previa (21,4041), abnormal amniotic fluid (19,21), prematurity (6,8,18,42), low birthweight for gestational age (7,8,10,11,24,42), large head circumference at birth ( 11,28,43) and forceps delivery (8). Birth trauma and birth asphyxia have also been reported as determinants of CP, but there is no agreement about their quantitative importance (4,5,8,20,21,26,(44)(45)(46)(47)(48)(49). Moreover, it cannot be documented with certainty in case-control studies whether statistical associations between either of these variables and CP reflect disease causation, uncontrollable information bias or consequences of the disease.…”
Section: Discussionmentioning
confidence: 99%