Birth by caesarean section and asthma

Conception via in vitro fertilization and delivery by Caesarean section are associated with paediatric asthma incidence

“…We have made allowance for the variety in municipalities and counties wherein the children resided, so as to address possible differences in local feeding/health habits; we also accounted for urbanity to refute potential perturbation of environmental factors in our analysis . We adjusted for low birth weight and short gestational age (SGA), both of which have been shown to promote asthma induction ; furthermore, IVF is associated with preterm and SGA infants which are also more likely to be delivered by C‐section . We controlled for single or multiple gestation as IVF can increase the risk of birth plurality which, in turn, predisposes for preterm delivery and low birth weight ; it also affects post‐neonatal health of the IVF offspring .…”

“…We adjusted for low birth weight and short gestational age (SGA), both of which have been shown to promote asthma induction [7,17,18,[38][39][40]; furthermore, IVF is associated with preterm and SGA infants [29,41] which are also more likely to be deliv- Association of Caesarean section and in vitro fertilization with paediatric asthma 1061 Values are expressed as n (%). ered by C-section [38]. We controlled for single or multiple gestation as IVF can increase the risk of birth plurality which, in turn, predisposes for preterm delivery and low birth weight [28]; it also affects post-neonatal health of the IVF offspring [26].…”

Early-term birth is a risk factor for wheezing in childhood: A cross-sectional population study

“…16 Because they also noted that ''the risk of asthma was also higher in children born by instrumental vaginal delivery,'' it is important to explore alternative explanations for future risk of wheeze, including the relative immaturity of the infants at birth, namely early-term birth (ie, 37-38 weeks' gestation). Other possible explanations include neonatal respiratory morbidity, such as transient tachypnea of the newborn, especially in those delivered by means of CS, 17 or family history of atopy because it might modify the risk of childhood respiratory symptoms, but there are few reports assessing its role in early term-born children.…”

Birth mode of delivery in the modern delivery ward – indication improves understanding of childhood asthma

“…Birth mode of delivery may affect outcomes such as asthma and allergic disease in children many years later. Recent meta-analyses have reported a 20% increase in the subsequent risk of asthma in children delivered by caesarean section (CS) [1,2] and a moderate risk increase for allergic rhinitis and asthma [3]. Some recent papers have reported children born with CS to have an increased risk of asthma [4][5][6], whereas others found no such associations [7][8][9][10].…”