Birth characteristics and acute otitis media in early life

Bentdal, Yngvild E.; Håberg, Siri E.; Karevold, Gunnhild; Stigum, Hein; Kværner, Kari J.; Nafstad, Per

doi:10.1016/j.ijporl.2009.11.001

Cited by 18 publications

(10 citation statements)

References 33 publications

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“…The elevated risk found for male children is in line with some of the literature[27,49], although the majority of published studies have been unable to find any association between early age OM and gender[11,15,28,48,50,51]. …”

Section: Discussionsupporting

confidence: 85%

Risk Factors of Early Otitis Media in the Danish National Birth Cohort

et al. 2016

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ObjectiveTo assess risk factors of otitis media (OM) in six-months-old children.MethodThe sample consisted of 69,105 mothers and their children from the Danish National Birth Cohort. The women were interviewed twice during pregnancy and again 6 months after birth. The outcome “one or more” maternal reported episodes of OM at age six months. In total 37 factors were assessed, covering prenatal, maternal, perinatal and postnatal factors.ResultsAt age six months 5.3% (95% CI 5.1–5.5) of the children had experienced one or more episodes of OM. From the regression analysis, 11 variables were associated with a risk of OM. When a Bonferroni correction was introduced, gender, prematurity, parity, maternal age, maternal self-estimated health, taking penicillin during pregnancy, and terminating breastfeeding before age six months, was associated with a risk of early OM. The adjusted ORs of OM for boys versus girls was 1.30 (95% CI 1.18–1.44). The OR having one sibling versus no siblings was 3.0 (95% CI 2.64–3.41). If the woman had been taking penicillin during pregnancy, the OR was 1.35 (95% CI 1.15–1.58). Children born before 38th gestational week had an increased OR for early OM of 1.49 (95% CI 1.21–1.82). Children of young women had an increased OR of early OM compared to children of older women. Additionally, children of women who rated their own health low compared to those rating their health as high, had an increased OR of 1.38 (95% CI 1.10–1.74). Finally, children being breastfeed less than 6 months, had an increased OR of 1.42 (95% CI 1.28–1.58) compared to children being breastfeed beyond 6 months.ConclusionThese findings indicate that prenatal factors are of less importance regarding early OM before the age of six months. Postnatal risk factors seem to pose the main risk of early OM.

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Section: Discussionsupporting

confidence: 85%

Risk Factors of Early Otitis Media in the Danish National Birth Cohort

et al. 2016

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“…Bentdal et al also found that the risk of acute otitis media in the first 18 months of age increased with decreasing GA when compared with infants born ≥37 weeks. [ 32 ] Similar to our results, the adjusted relative risk was higher for preterm infants compared with full term infants. [ 32 ]…”

Section: Discussionsupporting

confidence: 89%

“…[ 32 ] Similar to our results, the adjusted relative risk was higher for preterm infants compared with full term infants. [ 32 ]…”

Section: Discussionsupporting

confidence: 88%

Association of Gestational Age at Birth with Reasons for Subsequent Hospitalisation: 18 Years of Follow-Up in a Western Australian Population Study

et al. 2015

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BackgroundPreterm infants are at a higher risk of hospitalisation following discharge from the hospital after birth. The reasons for rehospitalisation and the association with gestational age are not well understood.MethodsThis was a retrospective birth cohort study of all live, singleton infants born in Western Australia between 1st January 1980 and 31st December 2010, followed to 18 years of age. Risks of rehospitalisation following birth discharge by principal diagnoses were compared for gestational age categories (<32, 32–33, 34–36, 37–38 weeks) and term births (39–41weeks). Causes of hospitalisations at various gestational age categories were identified using ICD-based discharge diagnostic codes.ResultsRisk of rehospitalisation was inversely correlated with gestational age. Growth-related concerns were the main causes for rehospitalisation in the neonatal period (<1 month of age) for all gestational ages. Infection was the most common reason for hospitalisation from 29 days to 1 year of age, and up to 5 years of age. Injury-related hospitalisations increased in prevalence from 5 years to 18 years of age. Risk of rehospitalisation was higher for all preterm infants for most causes.ConclusionsThe highest risks of rehospitalisation were for infection related causes for most GA categories. Compared with full term born infants, those born at shorter GA remain vulnerable to subsequent hospitalisation for a variety of causes up until 18 years of age.

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“…The increased RR of multiple TT procedures in cleft lip and/or palate group serves as a positive control for comorbidities in our study because the association with Eustachian tube dysfunction and need for repeat TT has been well established . Prematurity increases the risk of recurrent AOM in the first 18 months of life . The higher risk of multiple TT procedures may be related to overall smaller size and immaturity of the Eustachian tubes.…”

Section: Discussionmentioning

confidence: 86%

“…25 Prematurity increases the risk of recurrent AOM in the first 18 months of life. 26 The higher risk of multiple TT procedures may be related to overall smaller size and immaturity of the Eustachian tubes. Asthma also has been previously described as risk factor for AOM.…”

Section: Discussionmentioning

confidence: 99%