Birth order and the severity of illness in schizophrenia

Context:Ordinal position the child holds within the sibling ranking of a family is related to intellectual functioning, personality, behavior, and development of psychopathology.Aim:To study the association between birth order and development of psychopathology in patients attending psychiatry services in a teaching hospital.Settings and Design:Hospital-based cross-sectional study.Materials and Methods:Retrospective file review of three groups of patients was carried out. Patient-related variables like age of onset, birth order, family type, and family history of mental illness were compared with psychiatry diagnosis (ICD-10) generated.Statistical Analysis:SPSS 13; descriptive statistics and one-way analysis of variance (ANOVA) were used.Results:Mean age of onset of mental illness among the adult general psychiatry patients (group I, n = 527) was found to be 33.01 ± 15.073, while it was 11.68 ± 4.764 among the child cases (group II, n = 47) and 26.74 ± 7.529 among substance abuse cases (group III, n = 110). Among group I patients, commonest diagnosis was depression followed by anxiety and somatoform disorders irrespective of birth order. Dissociative disorders were most prevalent in the first born child (36.7%) among group II patients. Among group III patients, alcohol dependence was maximum diagnosis in all birth orders.Conclusions:Depression and alcohol dependence was the commonest diagnosis in adult group irrespective of birth order.

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“…A recent study pointed toward the possibility that later birth order results in a more severe form of schizophrenia. [21]…”

Section: Introductionmentioning

confidence: 99%

Birth Order and Psychopathology

Risal

Tharoor

2012

J Family Med Prim Care

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“…First, some studies found that higher birth order was associated with higher risk of neurodevelopmental disorders, such as schizophrenia. 5 6 Second, birth order has been reported to be related to grey matter volume. Comparing with first-born twins, second-born twins had smaller grey matter volume, indicating aberrant early brain development in the second-born twins, which could be also generalised to the singleton population.…”

Section: Discussionmentioning

confidence: 99%

“… 2–4 In particular, several studies have reported that higher birth order was associated with higher risk of neurodevelopmental disorders. 5 6 As an important part of early neurological development, a reduced level of stereoacuity has a negative impact on the ability of an individual to perform many tasks, thus leading to bad interactions with the world.…”

Section: Introductionmentioning

confidence: 99%

Effect of birth order on stereoacuity in Chinese preschool children: a cross-sectional study

Han

Zhang

et al. 2020

BMJ Open

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ObjectiveThis study aimed to investigate the relationship between birth order and stereoacuity among Chinese children aged 60–72 months.DesignCross-sectional.Participants1342 children with complete data on the questionnaire, stereoacuity and refraction were included.ResultsThe mean stereoacuity was 53.2±1.7, 56.9±1.9 and 60.9±1.5 s of arc in the first-born group, second-born group and third-born group, respectively. Lower birth order was significantly correlated with better stereoacuity (p=0.036). Third-borns (OR=3.02, p=0.027) were at higher risk of having subnormal stereoacuity compared with first-borns in the multivariate analysis.ConclusionLater-borns had poorer stereoacuity than first-borns.

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“…A number of contradictory results across both Western and non-Western literature have been reported in relation to birth order and age of onset of schizophrenia (Barry & Barry, 1967; Erlenmeyer-Kimling, 1969). Recent studies have largely explored the severity of the disorder with birth order (Gaughran, Blizard, Mohan, Zammit, & Owen, 2007). Reports from some non-Western countries indicate that higher frequency of schizophrenia was observed in late birth orders, contrary to reports from Western countries, which often note higher frequencies among firstborns (Bender, Azeem, & Morrice, 2000).…”

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confidence: 99%

Gender and obstetric factors in the determination of the age of onset of schizophrenia in a Nigerian cohort.

Afe

Adegbohun

Ogunsemi

et al. 2019

Journal of Abnormal Psychology

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The importance of gender and obstetric factors as predictors of the age of onset of schizophrenia is debatable. Unfortunately, there is a significant dearth of studies in developing countries such as Nigeria. This study involved a survey of patients with schizophrenia (n = 1,445; N = 2,393), from March 2014 to March 2016, from a psychiatric hospital in southwest Nigeria. Structured diagnostic interviews were used to confirm diagnosis. Females had a higher age of onset (M = 34.91, SD = 15.52) compared with males (M = 28.78, SD = 10.62; p = .00, M = 32.74 ± 12.96). Gender and marital status were the only variables significantly related to the age of onset (p = .00). Our model predicted 10.1% of the variability in the determination of the age of onset of schizophrenia.

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Birth order and the severity of illness in schizophrenia

Cited by 10 publications

References 25 publications

Birth Order and Psychopathology

Birth Order and Psychopathology

Effect of birth order on stereoacuity in Chinese preschool children: a cross-sectional study

Gender and obstetric factors in the determination of the age of onset of schizophrenia in a Nigerian cohort.

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