Birth outcomes among women with congenital neuromuscular disabilities

García, Michelle Huezo; Parker, Samantha E.; Petersen, Julie M.; Rubenstein, Eric; Werler, Martha M.

doi:10.1016/j.dhjo.2021.101259

Cited by 5 publications

(2 citation statements)

References 40 publications

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“…Additionally, we applied a weight variable to the data set to represent the approximate 3% national prevalence of major congenital anomalies. This reweighting approach is explained in further detail elsewhere (Huezo García et al, 2021; Richardson, Rzehak, Klenk, & Weiland, 2007). We present unweighted and weighted estimates for all analyses in supplemental tables (see Appendix).…”

Section: Methodsmentioning

confidence: 99%

“…Medication during pregnancy can be critical in maintaining the mother's health, but may lead to certain pregnancy complications. Understanding the prevalence of medication use during pregnancy among women with congenital physical disabilities is important to better recognize their specific health needs that may warrant clinical treatment, as well as assessing the cause of the increased risk of pregnancy complications common in this population (Huezo García, Parker, Petersen, Rubenstein, & Werler, 2021; Tarasoff, Ravindran, et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

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Medication use during pregnancy among women with congenital physical disabilities

García

Petersen

Parker

et al. 2022

Birth Defects Research

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Background Medication use during pregnancy is common, with up to 90% of pregnant women taking at least one medication. Women with congenital physical disabilities often report co‐occurring conditions during pregnancy that may warrant pharmaceutical treatment, however, research is limited. We aim to describe medication use during pregnancy including: pain, psychotropic, and antibacterial medication, among women with and without congenital physical disabilities. Methods We used data from the Slone Birth Defects Study (1976–2015), a case–control study that collected information on pre‐pregnancy health conditions and exposures among participating mothers. Women with congenital physical disabilities (n = 132) included women with spina bifida, cerebral palsy, muscular dystrophy, limb deficiencies, and other skeletal/connective tissue conditions and were matched by interview year and study site to women without congenital physical disabilities (n = 528). Proportions and difference in proportions for each medication were compared between groups. Simple proportions were also calculated for duration and multiple medication use variables. Results Women with congenital physical disabilities more frequently reported use of pain (acetaminophen and opioids), psychotropic (antidepressants), and antibacterial medications during pregnancy. Women with congenital physical disabilities used pain and psychotropic medications for longer, frequent durations, and more frequently reported haven taken multiple medications during pregnancy. Conclusion Women with congenital physical disabilities report higher medication use during pregnancy compared to women without physical disabilities. Patterns may be attributable to co‐occurring conditions or increased risk of pregnancy complications in this population. Further research is needed to describe the patterns of medication use for clinical decisions regarding treatment of pregnant women with disabilities.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%