Birth-Weight–Specific Infant Mortality Risks and Leading Causes of Death

Alo, Celan; Howe, Holly L.; Nelson, Merwyn R.

doi:10.1001/archpedi.1993.02160340071017

Cited by 11 publications

(4 citation statements)

References 1 publication

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“…Fetal or perinatal mortality, rather than survival of the low-birth-weight baby, was probably the norm before widespread availability of the modern-day newborn intensive care unit [21][22][23]. Small babies that did survive poor nutrition in utero were exceptional in some way, and the question remains as to what factor or factors facilitated Recent findings have sparked intense interest in birth weight as a predictor of type 2 diabetes mellitus.…”

Section: The Thrifty Genotype and Thrifty Phenotype Hypothesesmentioning

confidence: 99%

Birth weight as a predictor of type 2 diabetes mellitus: The U-shaped curve

Pettitt

Jovanovič

2001

Curr Diab Rep

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Recent findings have sparked intense interest in birth weight as a predictor of type 2 diabetes mellitus. In some populations, there is an inverse association between birth size and disease; however, in the Pima Indians, a population with very high rates of gestational diabetes, high birth weight and low birth weight are associated with diabetes. This results in a U-shaped curve with higher diabetes rates in both tails of the distribution. Similarly, there are reports of an inverse association between stature and prevalence of gestational diabetes, but, in California Latina women with gestational diabetes, there is a positive association between stature and glucose concentration. Could these disparate findings also represent the two ends of a U-shaped curve? The disparities are likely due to differences in the environment, both in utero and postnatally, that different groups experience.

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Section: The Thrifty Genotype and Thrifty Phenotype Hypothesesmentioning

confidence: 99%

Birth weight as a predictor of type 2 diabetes mellitus: The U-shaped curve

Pettitt

Jovanovič

2001

Curr Diab Rep

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“…[6][7][8] Among premature black infants, there also is a lower incidence of neonatal morbidity, such as respiratory distress syndrome and the need for neonatal assisted ventilation. 9,10 Similarly, the observed female advantage in survival among premature infants also may suggest a gender difference in illness severity, 8,11,12 although no gender difference in the incidence of threshold ROP was found in CRYO-ROP.…”

mentioning

confidence: 99%

Race, Gender, and Clinical Risk Index for Babies (CRIB) Score as Predictors of Severe Retinopathy of Prematurity

Yang

Donovan

Wagge

2006

Journal of American Association for Pediatric Ophthalmology and

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“…30 Deaths observed after the first month were 14% of the total; this value is in the 7± 17% range found in other studies. 1,4,5,31,32 The most frequent cause of death in this age interval was BPD. Infections and BPD are the likely consequence of the increasingly extensive use of intensive care techniques that prolong survival but expose the small and immunologically deficient babies to a high risk of acquiring severe nosocomial infections, BPD or both.…”

Section: Discussionmentioning

confidence: 92%

Clinical approach to the analysis of causes of death in the first two years of life of very‐low‐birthweight infants in a multicentre setting

Corchia

Spagnolo

Vonderweid

et al. 1997

Paediatric Perinatal Epid

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Mortality in the first 2 years of 634 very-low-birthweight infants admitted to eight neonatal intensive care units in Italy, and the factors associated with the net probability of death from each cause, were studied by means of the Cox proportional hazard model. A clinical classification of the causes of death was used. Overall mortality was 33.7% (intercentre range 12.6-52.9%). The highest cause-specific mortality rates were observed for respiratory problems, intra-ventricular haemorrhage (IVH) and infections (14.5%, 6.3% and 5.7% respectively). The leading causes of death were respiratory problems and IVH in the first week of life, infections from the second week up to the end of the first month, and bronchopulmonary dysplasia (BPD) afterwards. Birthweight < 1000 g, gestational age < 30 weeks, absence of spontaneous respiratory activity, unknown body temperature and pH < 7.20 at admission were associated with death from respiratory problems and IVH. Male sex, birthweight < 1000 g and unknown body temperature at admission were associated with death from BPD. Mortality from infections was higher in one centre; no other differences emerged among the eight NICUs. The classification of the causes of death employed and the use of the net probabilities of death appear as practical and useful instruments to study the relationship between specific aspects of medical care and mortality, and to investigate the reasons for differences in performance between neonatal units.

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Birth-Weight–Specific Infant Mortality Risks and Leading Causes of Death

Cited by 11 publications

References 1 publication

Birth weight as a predictor of type 2 diabetes mellitus: The U-shaped curve

Birth weight as a predictor of type 2 diabetes mellitus: The U-shaped curve

Race, Gender, and Clinical Risk Index for Babies (CRIB) Score as Predictors of Severe Retinopathy of Prematurity

Clinical approach to the analysis of causes of death in the first two years of life of very‐low‐birthweight infants in a multicentre setting

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