Bis-naphthalimides. 2. Synthesis and biological activity of 5,6-acenaphthalimidoalkyl-1,8-naphthalimidoalkyl amines

Synthesis and Photophysical Characterizations of Thermal -Stable Naphthalene Benzimidazoles

“…1,8-Naphthalimide and bisnaphthalimide derivatives are promising anticancer agents [9,10], the sulfonated derivatives are good antiviral agents with selective in vitro activity against the human immunity deficiency virus, HIV-1 [11]. Due to their photo-physical and photo-chemical properties the 1,8-naphthalimide derivatives can be used as fluorescence dyes for solar energy collectors and photosynthesis under concentrated sunlight [12], fluorescent markers in biological cells [13] as well as laser active media [14][15][16].…”

Synthesis and antioxidant, antimicrobial evaluation, DFT studies of novel metal complexes derivate from Schiff base

“…Creatinine is eliminated from the body by renal excretion at a relatively constant rate, making it a clinically chosen measurement to show renal function and a forensically chosen measurement to detect dilute urine and potentially adulterated specimens [19]. Some nitrogen heterocyclic compounds were reported to be antiparkinsonian [20], anticancer [21], antimicrobial [22]. Recently, density functional theory (DFT) has been accepted by the quantum chemistry community as a cost-effective approach for the computation of molecular structure, vibration frequencies, and energies of chemical reactions.…”

Poly(allylamine) Magnetomicelles for Image Guided Drug Delivery

“…The novel anticancer drug bisnaphthalimidopropyldiaminooctane (BNIPDaoct) has been reported to possess great potential as a cytotoxic agent in pancreatic cancer treatment [41,42]. BNIPDaoct has shown negligible aqueous solubility and as a result toxic solvents such as dimethyl sulfoxide (DMSO) have been required in order to dissolve the drug [41,43]. Here, we will investigate the potential of the two PAA derivatives in BNIPDaoct solubilisation using the optimal formulation strategies determined.…”