Bismuth Nanoparticles@Porous Silicon Nanostructure, Application as a Selective and Sensitive Electrochemical Sensor for the Determination of Thioridazine

Abstract

A bismuth@porous silicon (Bi/PSi) nanostructure is fabricated and used as a new highly sensitive electrochemical sensor for measurement of thioridazine. For this purpose, commercial silicon powder is converted to porous silicon using metal‐assisted chemical etching method. Then, bismuth nanoparticles are deposited on the surface of the porous silicon that synthesized in the previous step. The effects of pH and instrumental parameters are studied on the sensor response. After optimization of the parameters, differential pulse voltammetry is used to determine sub‐micro molar amounts of thioridazine. The Linear region of the electrochemical sensor is in the range of 0.1 to 260 μmol L−1 thioridazine with a detection limit of 0.03 μmol L−1, when Bi/PSi/CNTPE is used as an electrochemical sensor. The precision and accuracy of the sensor is evaluated. The Bi/PSi/CNTPE is used as an appropriated tool for accurate measurement of low amounts of thioridazine in real samples with satisfactory results.

Electrochemical Behaviour and Sensing of Chlorpromazine at Polymer‐Free Kaolin‐Based Nanosodalite and Nanosodalite‐Graphene Foam Film modified Glassy Carbon Electrodes

“…The modified electrodes were used to study the electrochemistry of CPZ aqueous media and it was observed that the electrochemical behaviour of CPZ depends on both the electrolyte pH and the nature of the electrodes. From this study, it was found MWCNT-PEI/ GCE DPV 0.019-9.2 0.01 [59] L-Cys-CPE DPV 1-35 0.0119 [60] P3MT/γ -CD/ GCE SWV 0.14-3.363 0.1 [27a] Bi/PSi/ MWCNT/CPE DPV 0.1-260 17 [61] ZnMnO that the electrochemical mechanism of the target analyte at the composite modified electrodes is either an Electrochemical-Electrochemical and Chemistry (EEC) mechanism or Electrochemical and Chemistry (EC) mechanism depending on the pH range while this mechanism is an EEC mechanism at SOD/GCE over the pH range studied. Both modified electrodes were used to sense chlorpromazine in aqueous media, SOD-GF/GCE exhibiting the highest sensibility due to the high surface area GF as well as the favorable π-π stacking interaction between graphene and of the aromatic group of CPZ.…”