Bispectral index monitoring to prevent awareness during anaesthesia: The B-aware randomised controlled trial

Dementia and sensitivity to anesthetics

“…Although the BIS monitor is in common use and may play a role in the prevention of intraoperative awareness and possibly other outcomes, [7][8][9][10] it is a limited measure of anesthetic-induced unconsciousness and brain function in general. It is well known that the BIS is relatively insensitive to the effects of anesthetics such as ketamine and nitrous oxide.…”

“…Bien que le moniteur BIS soit couramment utilisé et puisse jouer un rôle dans la prévention du réveil peropératoire et possiblement d'autres événements, 7 il s'agit d'une mesure limitée de l'état d'inconscience induit par l'anesthésique et de la fonction cérébrale en général. Nous savons bien que le BIS est relativement insensible aux effets d'anesthésiques comme la kétamine et le protoxyde d'azote.…”

‘Cooperative Sedation’: Optimizing Comfort while Maximizing Systemic and Neurological Function

“…Th e bispectral index allows for continuous monitoring of sedation with the benefi t of assigning an ordinal score to relative EEG wave form activity that lacks the subjectivity of the sedation scales. Th is technology has been used to assess depth of anesthesia in the operating room and has been shown, in that arena, to have reduced the number of episodes of intraoperative awareness [22]. Th e bispectral index has also been studied in the ICU in several populations of patients including medical, brain-injured and cardiac surgery patients and has been tested against several diff erent sedation scales, including the visual analog scales, the Ramsey scale, RASS and SAS [23][24][25][26].…”

An overview of quality and safety in health care

“…23 Large randomized controlled trials (RCTs) that address simple but important questions in clinical practice, with substantive patient outcomes as endpoints, are the cornerstone of advancing effectiveness in anesthesia; a number of excellent examples have been published in recent years. [33][34][35][36] The establishment of formal networks, such as the Outcomes Research Consortium, 37 the Australian and New Zealand College of Anaesthetists (ANZCA) Trials Group, 38 and the Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group 39 has substantially facilitated the conduct of large high-quality RCTs to provide reliable and clinically relevant evidence to guide the management of patients undergoing surgery or requiring critical care.…”

“…23 Des études randomisées contrôlées (ERC) d'envergure qui traitent de questions simples mais importantes dans la pratique clinique, avec comme critères d'évaluation des devenirs significatifs pour les patients, sont la pierre angulaire pour faire avancer l'efficacité en anesthésie; plusieurs excellents exemples ont été publiés au cours des dernières années. [33][34][35][36] …”