Bisphénol A et cancers hormono-dépendants

Rochefort, Henri

doi:10.1051/medsci/2013295019

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…Then, the evolution of plastics processing has been through several stages to meet plastic needs. Not only does plastic raise many environmental issues, but it also harms human health for its containing additives such as phthalates or bisphenol A (Groh et al 2019, Liu et al 2019, Piriou & Bouchaud 2018 which are considered to be endocrine disruptors; these, in turn, can cause toxic complications on the human health such as; endocrine disorders, neurological disorders, cancers, obesity, diabetes, infertility, allergic diseases like asthma and eczema (Groh et al 2019, Piriou & Bouchaud 2018, Rochefort 2013. To capitalize on an engagement plan for the fight against global warming, Morocco has implemented a new Moroccan law n°77-15 published in the Moroccan Official Bulletin N° 6422, which entered into force on 1 July, 2016 in order to ban the manufacture, marketing and import of plastic bags.…”

Section: Introductionmentioning

confidence: 99%

Socio-economic position of Chamaerops humilis L. var. argentea Andre in the province of Taza (North East Morocco) and impact of the new Moroccan law n° 77-15 (Moroccan Official Bulletin N° 6422) on the preservation of the environment

Lachkar¹,

Lamchouri

Toufik³

2020

Eth Res Appl

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Background: Chamaerops humilis L. var. argentea Andre is a species that exists in abundance in the province of Taza. It is a valuable source of income for the local population, which improves living conditions and reduces poverty. Hence, the importance of highlighting and quantifying the economic interest of this variety for the local population.Methods: In this regard, for the first time, a survey was conducted in the region to assess the socioeconomic importance of Chamaerops humilis, as well as the impact of the new Moroccan law n°77-15 on the ban of the use of plastic bags on its economic position. The study was carried out through a survey using 239 questionnaire sheets in five stations, conducted over two periods before (March-May, 2016) and after (November, 2016-March, 2017) the application of the new law.Results: Our study finds that Chamaerops humilis has a considerable economic value for the local population. The results showed that Chamaerops humilis is an important source of revenue through the sale of the palm heart (43.22 €/week/exploiter), and marketing of artisanal products (Doum baskets: 6.2 €/week/maker). Moreover, the application of the new law had a considerable impact on the basketry market, mainly on the marketing of Doum baskets (14.02 €/week/maker) to replace plastic bags.

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Section: Introductionmentioning

confidence: 99%

Socio-economic position of Chamaerops humilis L. var. argentea Andre in the province of Taza (North East Morocco) and impact of the new Moroccan law n° 77-15 (Moroccan Official Bulletin N° 6422) on the preservation of the environment

Lachkar¹,

Lamchouri

Toufik³

2020

Eth Res Appl

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Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells

Xin

Jiang

Liu

et al. 2014

Mutation Research/Genetic Toxicology and Environmental Mutagene

111

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Effect of bisphenol A on morphology, apoptosis and proliferation in the resting mammary gland of the adult albino rat

Ibrahim

Elbakry

Bayomy

2016

Int J Experimental Path

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SUMMARYBisphenol A (BPA) is a synthetic oestrogen that is extensively used in a wide range of daily used plastic products. This makes it one of the environmental chemicals that may have impact on human health. Due to its oestrogenic effect, BPA might affect the mammary gland. This study aimed to investigate the influence of BPA on the histological structure of the mammary gland of the adult female albino rat and its effect on epithelial cell proliferation and apoptosis status, in addition to its possible modulating effect on estrogen receptor expression. Thirty female adult albino rats were divided into control and experimental groups. The rats in the experimental group were gavaged with 5 mg/kg BPA daily for 8 weeks. The mammary glands were dissected and processed for histological and immunohistochemical stains for Ki-67, activated caspase-3 and estrogen receptor alpha (ER-a). BPA induced an increase in the number and size of the acini and ducts in the mammary gland of treated rats with hyperplasia of their lining epithelial cells. The collagen fibre content was significantly increased in the connective tissue stroma separating the ducts. Immunohistochemical results showed a significant increase in Ki-67 and caspase-3, but a nonsignificant increase in ER-a expression. Bisphenol A induced structural changes and affected the proliferation rate of mammary glands, so it might be one of the predisposing factors for breast cancer.

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Bisphénol A et cancers hormono-dépendants

Cited by 3 publications

References 22 publications

Socio-economic position of Chamaerops humilis L. var. argentea Andre in the province of Taza (North East Morocco) and impact of the new Moroccan law n° 77-15 (Moroccan Official Bulletin N° 6422) on the preservation of the environment

Socio-economic position of Chamaerops humilis L. var. argentea Andre in the province of Taza (North East Morocco) and impact of the new Moroccan law n° 77-15 (Moroccan Official Bulletin N° 6422) on the preservation of the environment

Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells

Effect of bisphenol A on morphology, apoptosis and proliferation in the resting mammary gland of the adult albino rat

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