Bitter taste genetics and oral health in Canadian Longitudinal Study on Aging
Marziyeh Shafizadeh,
Vikram Bhatia,
Samah Ahmed
et al.
Abstract:This study aimed to investigate the association of single nucleotide polymorphisms (SNPs) in 25 Bitter Taste Receptor genes (TAS2Rs) and 12 TAS2R pseudogenes with self-reported oral health outcomes in the Canadian Longitudinal Study on Aging (CLSA) cohort. Following quality control, 124 SNPs with a minor allele frequency > 0.01 and 21,991 individuals of European ancestry were included in the analysis. Fifteen SNPs in TAS2R8, 9, 13, 14, 20, and 50 were significantly associated with self-reported sore jaw mus… Show more
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