The theory of Fibonacci-circulant numbers was introduced by Deveci et al. (see [5]). In this paper, we define the Fibonacci-circulant-Hurwitz sequence of the second kind by Hurwitz matrix of the generating function of the Fibonacci-circulant sequence of the second kind and give a fair generalization of the sequence defined, which we call the generalized Fibonacci-circulant-Hurwitz sequence. First, we derive relationships between the generalized Fibonacci-circulant-Hurwitz numbers and the generating matrices for these numbers. Also, we give miscellaneous properties of the generalized Fibonacci-circulant-Hurwitz numbers such as the Binet formula, the combinatorial, permanental, determinantal representations, the generating function, the exponential representation and the sums.