Biventricular assessment of light-chain amyloidosis using 3D speckle tracking echocardiography: Differentiation from other forms of myocardial hypertrophy

Dataset on the use of 3D speckle tracking echocardiography in light-chain amyloidosis

“…The added material in this article extends and complements the data of the article entitled “Biventricular assessment of light-chain amyloidosis using 3D speckle tracking echocardiography: Differentiation from other forms of myocardial hypertrophy” (Vitarelli et al, 2018) [1] . Table 1 summarizes the conventional echocardiographic findings in patients, athletes and controls.…”

“…Full experimental design has been described elsewhere [1] , but in brief, twenty-three patients with light chain amyloidosis were studied. Subjects with hypertrophic cardiomyopathy(HCM), systemic arterial hypertension(HTN), and athlete's heart(ATHL) were also studied ( n =23 per group).…”

Biatrial and right ventricular deformation imaging: Implications of the recent EACVI consensus document in the clinics and beyond

“…The degree of disease severity is often judged by multichamber and pericardial involvement. 3D‐STE has been used to separate amyloid hypertrophy from other relatively benign forms of LV hypertrophy . Recently, Henein et al found in mutated transthyretin‐mediated amyloidosis that LA strain rate during atrial contraction was reduced independent of LA volume and could also predict atrial arrhythmias .…”

“…3D-STE has been used to separate amyloid hypertrophy from other relatively benign forms of LV hypertrophy. 10 Recently, Henein et al found in mutated transthyretin-mediated amyloidosis that LA strain rate during atrial contraction was reduced independent of LA volume and could also predict atrial arrhythmias. 31 As Figure 8 shows, a middle-aged subject had massive liver infiltration that required transplantation and was referred for an echo to exclude cardiac involvement.…”

“…The normative values of RV strain suggested by the American Society of Echocardiography (ASE) have been quite useful in the clinic as a complement to tricuspid annular plane systolic excursion (TAPSE) or fractional area change (FAC), the former being a routine tool, while the latter is infrequently used, though it could be valuable post–cardiac surgery or post–cardiac transplantation. As discussed later, diagnosis of an infiltrative form of cardiac amyloidosis can be confidently made using RV strain quantified by both 2D‐STE and three‐dimensional speckle tracking echocardiography (3D‐STE) . Moreover, RV free wall systolic strain (RVS) may predict sudden cardiac death or ventricular arrhythmias in subjects with acute myocardial infarction .…”